Factors Associated with Adherence to Medication in Major Depressive Disorder Patients

Authors

  • Kamonchanok Moonchai A student of Master of Nursing Science Program in Psychiatric and Mental Health Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Sopin Sangon Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Patcharin Ninthachan Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Malatee Rungrungsiripan Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University

Keywords:

major depressive disorder, beliefs about depression, beliefs about medicines, patient- healthcare provider relationships, medication adherence

Abstract

               Medication adherence is important for treatment of major depressive disorder (MDD). However, the rate of medication adherence is rather low. This descriptive correlational study aimed to investigate the association between gender, age, beliefs about depression, beliefs about medicine and patients, and the healthcare provider relationship with medication adherence in MDD patients. Eighty four MDD patients, both male and female, who received treatment at a psychiatric department of a community hospital were included in this study. The research instruments included a depression inventory, a personal data questionnaire, depression beliefs inventory,  beliefs about medicines questionnaire, the California Pharmacotherapy Alliance scale (patient version), and a medication adherence report scale. Descriptive statistics, point biserial correlation, and Spearman’s rank correlation were used for data analysis.

               Results showed that factors positively correlated with medication adherence in MDD patients were age (rs = .24, p < .05), beliefs about depression (rs = .45, p < .01), specific-necessity dimension of beliefs about medicines (rs = .32, p < .01), and patient-healthcare provider relationships (rs = .47, p < .01). Factors negatively correlated with medication adherence in MDD patients were beliefs about medicines-specific-concern dimension
(rs = -.27, p < .05), general - overuse dimension (rs = -.39, p < .01), and general-harm dimension
(rs = -.36, p < .01). However, gender had no relation with medication adherence (rs = .04, p > .05). The results from this study provide significant information to plan for promoting medication adherence in MDD patients.

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Published

2020-08-03

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บทความวิจัย (Research Report)