Effectiveness of using a practical care guideline to hypersensitivity reaction rate (HSRs) and length of stay (LOS) in patients who received paclitaxel carboplatin in Gynecologic ward Udonthani Hospital

Abstract

This quasi-experimental research aimed to compare hypersensitivity reaction rate (HSRs) and length of stay (LOS) of gynecologic patients who received paclitaxel carboplatin between group who used and did not use the Clinical Nursing Practical Guideline. The participants recruited from patients who had admitted in the gynecologic ward, Udonthani Hospital. The samples were purposive sampling for 60 patients; 30 peoples per group who used and did not used the guideline.

Method : Collected demographic data, history of illness, treatment and hypersensitivity record by questionaires. The instruments were a handbook of self-caring while receiving paclitaxel carboplatin and a practical care guideline for patients who received paclitaxel carboplatin. The data was collected from 1st May to 30th September 2015. Descriptive statistics was applied on demographic data. Comparing the HSRs and LOS between groups was analyzed on SPSS 16.0 by using Chi-square and Mann Whitney U- test

Results showed that the majority of participants were married and housewife, age 40– 59 years old. Level of education was primary school. Approximately 40% of both groups were diagnosed of 1st stage of cancer receiving the first course of chemotherapy. Their ECOG SCORE were 0-1 who could do normal activities in daily living and had no symptom of illness. Comparison of HSRs between groups revealed that the participants who used the practical care guideline had HSRs higher than the other group 70.0% and 10.0% respectively with statistically significant (p = .000). There was no statistically difference between groups on the LOS (p = 1.0). Then longitudinal study to investigate the effectiveness of the guideline to reduced HSRs was recommended.