Survival Rate and Factors Affecting on Survival in Patients with Infective Endocarditis Undergoing Surgery in Udonthani Hospital
Keywords:
Survival rate, patients with Infective Endocarditis, factorsAbstract
This retrospective descriptive study aimed to investigate the 1 year survival rates and factors influence the survival of patients who underwent surgery for infective endocarditis (IE) at Udonthani Hospital, during 2019, January 1st to 2022, August 30th. Patients were continuous follow-up until their end-of-life status, extending until August 30, 2023. Data were collected by comprehensive review of medical records containing baseline characteristics, demographic information during surgical treatment of infective endocarditis (IE), data related to cardiopulmonary bypass (CPB) and ultrafiltration, and post-operative results. The gathered data were analyzed using descriptive statistics and inferential statistics, including the Log-rank test and Cox regression analysis to elucidate factors influencing patient survival.
The study, involving 105 patients undergoing surgery for infective endocarditis, Postoperative survival was 93.33% at 30 days, 89.53% at 3 months, 88.58% at 6 months 6 and 87.48% at 1 year. Factors predicting 1-year mortality determined by multiple Cox regression analysis, were as follows: the use of modified ultrafiltration (MUF) as a surgical method (Adjusted HR = 5.44; 95%CI: 1.38-21.44, p = 0.016), female gender (Adjusted HR = 6.68; 95%CI: 1.71-26.04, p = 0.006), pulmonary complications (Adjusted HR = 9.50; 95%CI: 2.62-34.44, p =0.001), and renal failure (Adjusted HR = 5.79; 95%CI: 1.41-23.72, p=0.01)
In conclusion, survival rates following surgery for infective endocarditis were observed at 30 days (93.33%), 3 months (89.53%), 6 months (88.58%), and 1 year (87.48%). Factors associated with mortality within the first-year post-surgery included the use of modified ultrafiltration (MUF) as a surgical method, female gender, pulmonary complications and renal failure.
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