Impact of 1-Hour sepsis bundle Compliance on 30-Day Mortality Among Adult With Community-Acquired Sepsis and Septic Shock in Banphue Hospital
Keywords:
1- hour sepsis bundle, 30-day mortalityAbstract
1-hour sepsis bundle is recommended in Surviving Sepsis Campaign (SSC) Guideline 2018. Latest update of SSC guideline was revised and released in 2021. Many studies have shown lower mortality in compliance with 3-hour sepsis bundle, but supporting evidence on 1-hour sepsis bundle were scarcely published. The objective of this research was to study impact of 1-hour sepsis bundle compliance on 30-day mortality among adult with community-acquired sepsis and septic shock in Banphue hospital. This retrospective descriptive study used target group of patients with sepsis and septic shock who were admitted to Banphue hospital and selected by purposive sampling method. 119 patients with sepsis and septic shock from April 2022 to March 2023 were included in the study. Data collection used case record from as secondary data from the electronic database of Banphue hospital and research tools included clinical practice guideline sepsis, septic shock fast track, SOS score, complete 1-hour bundle record. Data were analyzed using descriptive statistic; percentages, means, standard deviations and inferential statistics analysis using Chi- square, t test and logistic regression.
Results: 119 patients were enrolled in the study. Most of them were male (61.34%). The average age was 59.24 years old. The most source of infection was pneumonia. The ventilator used was 21.85%.The 30-day mortality was 31.09%. The 30-day mortality in complete and incomplete implementation of the 1-hour sepsis bundle were 28.95 and 34.88%, respectively. There was no statistical difference (p=0.60). No factors that significantly affected the mortality was found.
Conclusions: The 30-day mortality in the complete implementation of 1-hour sepsis bundle is slightly less than the incomplete implementation group, but the reduction was not statistically significant. Further research should be identify the factors contributing to increased compliance with the 1-hour sepsis bundle and to study factors affecting the 30-day mortality of patients with sepsis.
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