Factors Associated with Cervical Cone Margin after Loop Electrosurgical Excision Procedure (LEEP) in Women with Cervical Intraepithelial Neoplasia at Uttaradit Hospital

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Published: Mar 23, 2020
Keywords:
Cervical intraepithelial neoplasia, Loop Electrosurgical Excision Procedure, cervical cone margin

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Narisa Jenrungrojsakul
Department of Obstetrics-Gynecology Uttaradit Hospital, Uttaradit Province

Abstract

This study retrospective cohort study was to investigate the factors associated with cervical cone margin after Loop Electrosurgical Excision Procedure (LEEP) in women with cervical intraepithelial neoplasia. The data were collected from medical records among 229 patients with cervical intraepithelial neoplasia after LEEP at Uttaradit Hospital during January 2015 to April 2019. Descriptive statistics and multiple logistic regression were used in this study. Results showed that the factors associated with cervical cone margin after LEEP were cervical cytology of SCCA (Adj. OR= 7.89; 95%CI: 2.73-16.87), grade of disease at invasive SCC (Adj. OR= 7.55; 95%CI: 1.81-27.42), glandular involvement (Adj. OR= 3.51; 95%CI: 1.90-6.21), size of disease at 2 quadrant (Adj. OR= 6.10; 95%CI: 2.66-16.32), 3 quadrant (Adj. OR= 6.78; 95%CI: 3.61-14.91), and 4 quadrant (Adj. OR= 9.56; 95%CI: 1.89-20.32). This study found that factors associated with cervical cone margin after LEEP were statistically significant with cervical cytology of SCCA, grade of disease at invasive SCC and glandular involvement on pathology and size of disease more than one quadrant in cervical of patient.

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1.
Jenrungrojsakul N. Factors Associated with Cervical Cone Margin after Loop Electrosurgical Excision Procedure (LEEP) in Women with Cervical Intraepithelial Neoplasia at Uttaradit Hospital. Health Sci J Thai [Internet]. 2020 Mar. 23 [cited 2024 Apr. 27];2(1):9-20. Available from: https://he02.tci-thaijo.org/index.php/HSJT/article/view/240067
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Vol. 2 No. 1 (2020): January - April 2020
Section
Original articles

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