Drug Resistance Testing of HIV Patients/Aids Antiviral HIV Drugs Treatment at Roi Et Hosptival: A Retrospective Study

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Published: Mar 29, 2021
Keywords:
HIV patients/Aids HIV-Viral load HIV-Drug Resistance

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Preeyapat Treeboonmuang
Department of Molecular Biology, Roi Et Hospital, Roi Et Province
Nuntiput Putthanachote
Department of Clinical microbiology, Roi Et hospital, Roi Et province, Thailand.

Abstract

The objective of this retrospective descriptive study was to study the result of drug resistance testing among HIV/AIDS patients receiving antiviral HIV drugs treatment. The study subjects were HIV/ADIS patients having HIV-Viral Load (VL) >1,000 copies/mL. The data was collected by the molecular laboratory at Roi Et Hospital between January 1st, 2016 to December 31st, 2018. The data was analyzed using descriptive statistics. The results showed that two-thirds of patient were males (64.36%), average age 35.09 years (SD = 11.23). The average HIV-VL was 102,795.6 copies/mL (±SD 215,831.6). Two-thirds of subjects had drug resistance (68.88%) consisting of Nucleoside Reverse Transcriptase Inhibitors (NRTIs) (45.21%), Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) (65.69%), and Protease Inhibitors (PIs) (3.99%). It showed that all of them susceptible to Integrase strand transfer Inhibitors (INSTIs) (100%) and resistance to NRTIs (1.44%), NNRTIs (2.09%) and PIs (0.13%). It was found that there was non-resistance to INSTIs drug. In summary, most patients had drug resistant to NNRTIs, NRTIs
and Pls and susceptible to INSTIs

Article Details

How to Cite
1.
Treeboonmuang P, Putthanachote N. Drug Resistance Testing of HIV Patients/Aids Antiviral HIV Drugs Treatment at Roi Et Hosptival: A Retrospective Study. Health Sci J Thai [Internet]. 2021 Mar. 29 [cited 2024 Nov. 22];3(1):10-6. Available from: https://he02.tci-thaijo.org/index.php/HSJT/article/view/241163
Issue
Vol. 3 No. 1 (2021): January - April 2021
Section
Original articles

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