Risk Factor Associated with Pneumonia and Mortality in Patients with Nosocomial COVID-19 Infection in a Tertiary Care Hospital, Southern Thailand

Main Article Content

Watjanarat Nitchot

Abstract

In Hatyai Hospital, the outbreak of nosocomial COVID-19 occurred in August 2021. The majority of patients with nosocomial COVID-19 infection have underlying diseases resulting increase mortality. This study aimed to study factors associated with mortality in patients with nosocomial COVID-19 infection, causes and factors related to nosocomial COVID-19 pneumonia in Hatyai Hospital. A retrospective cohort study is collecting patients with nosocomial COVID-19 in the Hatyai Hospital, from 1st August 2021 to 31st March 2022. The data analysis method using the SPSS program reported correlation size of data with odd ratio. Analyze variable correlation by the Multivariable logistic regression method. The data were statistically different when the p-value < 0.05. 102 patients with nosocomial COVID-19 in Hatyai Hospital. Factors affecting pneumonia were age over 60 years, having the underlying disease, and having symptoms, which were statistically significant. The cause of nosocomial COVID-19 infection was relatives or bedside patients side-by-side and inconclusive. The risk factors associated with mortality were hematologic disease and pneumonia, which were statistically significant. In conclusion, factors affecting pneumonia were age over 60 years, having the underlying disease, and having symptoms. The cause of nosocomial COVID-19 infection was relatives or bedside patients side-by-side and inconclusive. The findings of this study are useful for close monitoring in nosocomial COVID-19 with hematologic disease and pneumonia.

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How to Cite
1.
Nitchot W. Risk Factor Associated with Pneumonia and Mortality in Patients with Nosocomial COVID-19 Infection in a Tertiary Care Hospital, Southern Thailand. Health Sci J Thai [Internet]. 2023 Jul. 17 [cited 2024 Dec. 22];5(3):80-7. Available from: https://he02.tci-thaijo.org/index.php/HSJT/article/view/260980
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Original articles

References

Department of Disease Control. Report of Coronavirus Disease 2019 (COVID-19). [Internet] 2019 Available

from: https://ddc.moph.go.th/viralpneumonia/situation.php

World Health Organization. Infection prevention and control during health care for probable or confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection: [Internet] 2019 [Cited 17 January, 2020] Available from: https://apps.who.int/iris/handle/10665/174652

WHO guidelines on hand hygiene in health care: first global patient safety challenge – clean care is safer care. Geneva: World Health Organization: [Internet] 2009 [Cited 17 January, 2020] Available from https://apps.who.int/iris/handle/10665/44102

Rhee C, Baker M, Vaidya V, Tucker R, Resnick A, Morris CA, et al. Incidence of Nosocomial COVID-19 in Patients Hospitalized at a Large US Academic Medical Center. JAMA Netw Open 2020 Sep; 3(9): e2020498.

Khan KS, Reed-Embleton H, Lewis J, Saldanha J, Mahmud S. Does nosocomial COVID-19 result in increased 30- day mortality? A multi-centre observational study to identify risk factors for worse outcomes in patients with COVID-19. Journal of Hospital Infection 107 2021; 91-95.

Wuttayakorn T, Sithisarankul P. Risk factors for COVID-19 Infection. Journal of Preventive Medicine Association of Thailand 2021; 11(2): 447-464.

Gesesew HA, Koye DN, Fetene DM, Woldegiorgis M, Kinfu Y, Geleto AB, et al. Risk Factors for COVID-19 infection disease severity and related deaths in Africa: a systematic review. BMJ Open 2021; 11: e044618.

Dessie Z and Zewotir T. Mortality-related risk factors of COVID-19: a systematic review and meta-analysis of 42 studies and 423,177 patients. BMC Infect Dis 2021; 21: 855.

Cueto-Manzano AM, Espinel-Bermúdez MC, Hernández-González SO, Rojas-Campos E, Nava-Zavala AH, Fuentes-Orozco C, et al. Risk factors for mortality of adult patients with COVID-19 hospitalised in an emerging country: a cohort study. BMJ Open 2021; 11: e050321.

Mamo J, Feroz B, Mahmood S. Covid-19: protecting patients in hospital for neurorehabilitation and their therapists. BMJ 2020; 369: m1630.

Thomas JP, Srinivasan A, Wickramarachchi CS, Dhesi PK, Hung YM, Kamath AV. Evaluating the national PPEguidance for NHS healthcare workers during the COVID-19 pandemic. Clin Med 2020; 20: 242–7.

Jewkes S, Zhang Y, Nicholl D. Nosocomial spread of COVID-19: lessons learned from an audit on a stroke/neurology ward in a UK district general hospital. Clinical Medicine 2020; 20(5): e173-7.

Sun H, Lu M, Chen S, Cheng Z, Xiong Y, Wang X. Nosocomial SARSCoV-2 infection among nurses in Wuhan at a single centre. J Infect 2020; 80(6): e41–2.

Wei XS, Wang XR, Zhang JC, Yang WB, Ma WL, Yang BH, et al. A cluster of health care workers with COVID-19 pneumonia caused by SARSCoV-2. J Microbiol Immunol Infect 2020; S1684-1182(20): 30107-9.

Abbas M, Nunes T, Martischang R, Zingg W, Iten A, Pittet D, et al. Nosocomial transmission and outbreaks of coronavirus disease 2019: the need to protectboth patients and healthcare workers. Antimicrob Resist Infect Control 2021; 10: 7.

Carter B, Collins JT, Barlow-Pay F, Rickard F, Bruce E, Verduri A, et al. Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial Study (COVID in older People). Journal of Hospital Infection 2020; 10(6): 376-384.

Department of Medical Services. Guidelines for clinical practice, diagnosis, treatment and prevention of hospital infection Coronavirus disease 2019 (COVID-19); [Internet] 2022 Available from: https://covid19.dms.go.th/Content/Select_Landding_page?contentId=178

Aghdassi SJ, Schwab F, Peña Diaz LA, Brodzinski A, Fucini GB, Hansen S, et al. Risk Factors fo nosocomial SARS-CoV-2 infections in patients:results from a retrospective matched case-control study in a tertiary care university center. Antimicrobial Resistance and Infection Control 2022; 11: 9.