The Outcomes of Proactive Breast Cancer Screening for Women at Risk Aged 30-70 Years Old, Using Mammograms and Breast Ultrasounds in Phanom Sarakham District, Chachoengsao Province

Abstract

Objectives: to evaluate the outcomes of breast cancer screening classified according to the BIRADS (category 1–5) among at-risk women and to estimate the prevalence of breast cancer. Factors associated with BIRADS 4-5 among this group was also determined.

Methods: a cross-sectional study using secondary data of women at risk who participated in proactive breast cancer screening was conducted. The proportion of BIRADS 1-5 and the prevalence of breast cancer were presented as percentages. Multivariable log-binomial regression analysis was performed to determine factors associated with BIRAD4-5 and presented as an adjusted prevalence ratio (APR) with a 95% confidence interval (CI).

Results: A total of 2,501 participants, with a mean age of 54.5 (+ 9.8) years, were included in the analyses. The proportion of BIRADS 1, 2, 3, 4, and 5 was 72.0, 22.0, 4.4, 1.3, and 0.3 percents, respectively. The prevalence of BIRADS 4-5 and breast cancer was 1.6% (95% CI: 1.2-2.2) and 0.8% (95% CI: 0.5-1.2), respectively. Factors associated with BIRADS 4-5 included women presenting with a palpable mass in the breast or axilla (aPR 5.73; 95% CI: 3.12-10.54), and those whose first childbirth occurred after the age of 35 (aPR 2.60; 95% CI: 1.21-5.57).

Conclusion: We highlighted the benefits of proactive breast cancer screening using BIRADS, analyzing the prevalence of breast cancer and factors associated with high-risk groups (BIRADS 4-5). This evidence aims to guide policymakers in developing a proactive screening system for at-risk women, ensuring access to standardized services, and promoting early detection of breast cancer.