Effects of a Renal Deterioration Delay Program on Knowledge and Clinical Outcomes among Patients with Type 2 Diabetes Mellitus and Hypertension with Stage 3 Chronic Kidney Disease at Nong Bua Daeng Hospital, Chaiyaphum Province

Abstract

This one-group quasi-experimental study with a pretest–posttest design aimed to examine the effects of a renal deterioration delay program on knowledge and clinical outcomes among patients with type 2 diabetes mellitus and hypertension who had stage 3 chronic kidney disease. The study was conducted from July to September 2025. Samples consisted of 260 patients with type 2 diabetes mellitus and hypertension with stage 3 chronic kidney disease at Nong Bua Daeng Hospital, Chaiyaphum Province, selected through the purposive sampling. Research instruments included a knowledge assessment questionnaire on self-care for delaying kidney deterioration and clinical outcome measurements. Data were analyzed using the paired t-test, with the level of statistical significance set at 0.05.

The results revealed that, after receiving the renal deterioration delay program, the samples showed a significant increase in knowledge regarding self-care for delaying kidney deterioration (p<0.05). Clinical outcomes, including systolic blood pressure, diastolic blood pressure, and Hemoglobin A1c, were significantly reduced (p<0.05). In addition, analysis of kidney function using serum creatinine and estimated glomerular filtration rate indicated that, after participation in the program, there were no significant differences in serum creatinine and estimated glomerular filtration rate compared to before the program.

These findings suggest that the renal deterioration delay program is effective in the care of patients with diabetes and hypertension, as it can slow the progression of kidney deterioration and reduce glycated hemoglobin levels and blood pressure. Therefore, the program should be implemented in other areas in the future.