Treatment of Multiple Facial Flat Warts with 5%Imiquimod Cream

Authors

  • Walleya Mekasuwundit CHACHOOENGSAO HOSPITAL, CHACHOOENGSAO, THAILAND

Keywords:

multiple facial flat warts, 5% imiquimod cream

Abstract

Imiquimod is a unique topical therapeutic agent useful in the treatment of external genital and perianal warts (condyloma acuminata) in adult. The author report a case of 26-year –old man who experienced complete clearance of multiple facial flat warts after 4 weeks of therapy with topical imiquimod 5% cream and glycolic soap.

References

Androphy EJ, Beutner K, Olbrichr S: Human papillomavirus infection. In: Cutaneous Medicine and Surgery: an intergrated Program in Dermatology (Amdt KA, Leboit PE, Robinson JK, et al., eds), pp 1100-17 . Philadelphia, WB Saunders Company, 1996.

Stone MS, Lynch PJ. Viral warts. In: Principles and Practice of Dermatology, (Sams WM jr., Lynch PJ, eds) ed 2, pp 127-32 .New York, Churchill Livingstone 1996.

Webster GF, Satur N, Goldman MP, Halmi B, Greenbaum S. Treatment of recalcitrant warts using the pulsed dye laser. Cutis 1995; 56: 230-2.

Wagstaff AJ, Perry CM. Topical imiquimod: a review of its use in the management of anogenital warts, actinic keratoses, basal cell carcinoma and other skin lesions. Drugs 2007; 67: 2187-210.

Edwards L, Ferenczy A, Eron L, et al. Self-administered topical 5% imiquimod cream for external anogenital warts: HPV Study Group: Human PapillomaVirus. Arch Dermatol 1998; 134: 25-30.

Weeks EC, Gibson SJ. Induction of interferon and other cytokines by imiquimod and its Hydroxylated metabolite R-842 in human blood cells in vitro. Interferon Res 1994; 14: 81-85.

Beutner KR, Tyring SK, Trofatter KF Jr., et al. Imiquimod a patient-applied immune-response modifier for treatment of external genital warts. Antimicrob Agents Chemother 1998; 42: 789-94.

Schöfer H, Van Ophoven A, Henke U, Lenz T, Eul A. Randomized, comparative trial on the sustained efficacy of topical imiquimod 5% cream versus conventional ablative methods in external anogenital warts. Eur J Dermatol 2006; 16: 642-8.

Griffiths CE, Voorhees JJ, Nickoloff BJ. Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal and inflamed skin: modulation by recombinant gamma interferon and tumor necrosis factor. J Am Acad Dermatol 1989; 20: 617-29.

Suzuki H, Wang B, Shivji GM, et al. Imiquimod a topical immune response modifier induces migration of Langerhans cells. J Invest Dermatol 2000; 114: 135-41.

Schwab RA, Elston DM. Topical imiquimod for recalcitrant facial flat warts. Cutis 2000; 65: 160-2.

Bacelieri R, Johnson SM. Cutaneous warts: an evidence-based approach to therapy. Am Fam Physician 2005; 72: 647-52.

Oster-Schmidt C. Imiquimod: a new possibility for treatment – resisitant verrucae planae. Arch Dermatol 2001; 137: 666-7.

KhanDurani B, Jappe U. Successful treatment of facial plane warts with imiquimod. Br J Dermatol 2002; 147: 1018.

Nagington J, Rook A, Highet AS. Virus and related infections. In: Textbook of Dermatology. Rook A, Wilkinson DS, Ebling FJG, Champion RH, Burton JL eds. 4th ed. Oxford: Blackwell Scientific Publications 1986: 657-723.

Downloads

Published

2026-07-02

How to Cite

Mekasuwundit, W. (2026). Treatment of Multiple Facial Flat Warts with 5%Imiquimod Cream. Thai Journal of Dermatology, 24(2), 113–118. retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/283390

Issue

Section

Case Report