An Effect of a Low Dose Aspirin on An Immediate Post- Operative Bleeding of Simple Tooth Extraction
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Abstract
Objectives: To determine the complete tooth socket hemostasis rate at 10, 15, 20, 25, and 30 minutes after tooth extraction and the hemostasis related complications in patients who are receiving aspirin within 24 hours after tooth extraction.
Materials & Methods: The prospective descriptive study was done in patients taking aspirin as antithrombotic agent who required a single tooth extraction. The tooth extraction was performed under local anesthesia without the aspirin holding. Hemostasis was obtained by gauze bitten over the tooth socket. The outcome assessment was evaluated by observing the evidence of clinical bleeding in the socket area in 10 minute-time after extraction and every 5 minutes interval until 30 minutes after the extraction. However, the patients were requested to stay and reassessed any related complications within 1 hour. The follow up period was extended to 24 hours by phone as well.
Results: A total of 60 patients with mean age of 66.3 (43-80) years were included. The majority were molar teeth (51.7%) and pulp necrosis (38.3%). The bleeding from tooth socket which was settled within 10 minute-time was 58.3%, within 15 minute-time was 83.3%, and within 20, 25, 30 minute-time were 98.3% equally. There was only one patient who detected blood oozing at tooth socket after 30 minutes. The hemostasis was completed within 5 minutes by suture technique.
Conclusion: The time dependent hemostasis rate of the tooth socket in patients who taking aspirin after tooth extraction was 58.3% within 10-minute interval and most of the patients’ hemostasis (98.3%) was achieved within 20 minutes, without re-bleeding or any other complications.
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References
ปริศนา ปริพัฒนานนท์. การดูแลผู้ป่วยถอนฟัน. ใน: ปริศนา ปริพัฒนานนท์ , พิชัย วิทยากิตติพงษ์.การถอนฟัน พิมพ์ครั้งที่ 5. สงขลา:โรงพิมพ์นำผล; 2549.หน้า109.
Hupp JR. Postoperative patient management.In:James R. Hupp,Edward Ellis III,Myron R. Tucker. Contemporary oral and maxillofacial surgery.5thed.n.p.:Mosby;2008.p179.
Thomson FM, Exodontia.In:Fernando Solé Besoaín , Francisco Muñoz Thomson. Oral surgery for undergaduates & general practitioners. New Delhi: Medtec;2013.p.280.
Borle Rajiv M,Arora Aakash,Magarkar Shashwat D.Exodontia.In:Rajiv M Borle,editor.Textbook of oral and maxillofacial surgery.1sted.Kundli:Sanat Printers ;2014.p.209.
ลลิตกร พรหมมา.ข้อปฏิบัติหลังถอนฟัน ในการถอนฟันทางปฏิบัติ.ครั้งที่1.กรุงเทพฯ:สำนักพิมพ์แห่งจุฬาลงกรณ์ มหาวิทยาลัย; 2558.หน้า211.
แนวทางเวชปฏิบัติกลุ่มงานทันตกรรม โรงพยาบาลกลาง กรุงเทพ.2564หน้า1-4.
Practical Haemostasis(Internet).Cambridge:Sang Medicine;2019.update 2022 Sep 27;cited 2022 Nov 05. Avialable from: https://www.practical-haemostasis.com /Miscellaneous/bt.html
Nagraj SK, Prashanti E , Aggarwal H, et.al. Interventions for treating post-extraction bleeding. Cochrane Database of Systematic Reviewer; 2018: 3. Art. No:CD011930. DOI: 10.1002/146518. CD011930.pub3.
Friberg L, Rosenqvist M, Lip G.Y.H. Evaluation of risk stratification schemes for ischaemic stroke and bleeding in 182678 patients with atrial fibrillation the Swedish atrial fibrillation cohort study. Eeuropean Heart Journal.2012;33:1500-1510.
Oprea A.D, et al. Perioperative management of antiplatelet therapy. Br J Anaesth.2013;111: 3-17.
Dézsi C.A.,Dézsi B.B.,Dézsi A.D. Management of dental patients receiving antiplatelet therapy or chronic oral anticoagulation: A review of the latest evidence. European Journal of General Practice.2017:23:196- 201.
Saez-Alcaide L.M, Sola-Martin C, Molinero-Mourelle P, Paredes-Rodriguez V, Zarrias-Caballero C, Hernandez-Vallejo G. Dental management in patients with antiplatelet therapy A systematic review. J Clin Exp Dent.2017:9(8):e1044-50.
กิจธนัสถ์ เชียงเงินธัญกุล. ยาต้านเกล็ดเลือดและยาต้านการแข็งตัวของเลือดกับการรักษาทางทันตกรรม บทความปริทัศน์. วิทยาสารทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่น 2561;21:189-204.
Lillis T, Ziakas A, Koskinas K, Tsirlis A.,Giannoglou G. Safety of dental extractions during uninterrupted single or dual antiplatelet treatment. Am J Cardiol2011;108:964-967.
Sanchez-Palomno P, Sanchez-Cobn P, Rodriguez-Archilla A, Gonzalea-Jaranay M. Moreu G, Calvn-Guirado JL, et al. Dental extraction in patients receiving dual antiplatelet therapy. Med Oral Patol Cir Bucal.2015;20:616-20.
Dinkova AS ,Atanasov DT ,Vladimirova-Kitova LG .Discontinuation of oral antiplatelet agent before dental extraction – necessity or myth?. Folia Medica 2017;59:336-43.
Lu S.Y., Lin L.H., Hsue S.S. Management of dental extractions in patients on warfarin and antiplatelet theray. J of the Forosan Medical Association.2018;117:979-86.
Scottish Dental Clinical Effectiveness Programme (SDCEP).2015. Management of dental patients taking anticoagulants or antiplatelet drugs. Dental Clinical Guidance. Available from: http://www.sdcep.org.uk/wp-content/uploads/2015/09/SDCEP-Anticoagulants-Guidance.pdf.
Darawade DA, Kumar S, Desai K, Hasan B, Mansata AV. Influence of aspirin on postextraction bleeding a clinical study. J Int Soc Prev Community Dent 2014;4(4):63-67.
Kumar S, Paul A, Chacko R, Deepika S. Time Required for Haemostasis under Pressure from Dental Extraction Socket. Indian J of Dent Res. 2019;30:894-8.
นฐธิกานต์ เจริญรัตนเดชะกูบ,วริยา สุขุประการ. ประสิทธิผลของการใช้แผนภาพเพื่อเป็นแนวทางสำหรับบุคลากรวิสัญญีในการประเมินการสูญเสียเลือดด้วยสายตาระหว่างการผ่าตัดในโรงพยาบาลมหาราชนครเชียงใหม่. วิสัญญีสาร 2560;43:27-39.
Chow SC, Shao J,Wang H. Sample size calculations in clinical research(2nd). Chapman&CRC.83.
Bidet L.,Weinstein J.M. Baumagarten A.K. Efficacy of fibrin sealant in patients on various levels of oral anticoagulant undergoing oral surgery. Oral Surgery Oral Med Oral Pathol Oral Radiol Endod.1998;86:421-3.
Eapen B.J., Baig M.F., Avinash S. An Asessment of the Incidence of Prolonged Postoperative Bleeding After Dental Extraction Among Patients on Uninterrupted Low Dose Asprin Therapy and to Evaluate the Need to Stop Such Medication Prior to Dental Extractions. J.Maxillofac.Oral Surg.2017;16:48-52.
Lillis T, Didagelos M, Lillis L,Theodoridis C,Karvounis H,Ziakas A. Impact of post-exodontia bleeding in cardiovascular patients a new classification proposal. The Open Cardiovascular Medicine Journal.2017;11:102-110.
De Campos, N. , Furlaneto, F. , De Paiva Buischi, Y. Bleeding in Dental Surgery. In: Firstenberg, M. S. , Stawicki, S. P. , editors. Contemporary Applications of Biologic Hemostatic Agents across Surgical Specialties - Volume 2 [Working Title] [Internet]. London: IntechOpen; 2019 [cited 2022 Nov 06]. Available from: https://www.intechopen.com/online-first/69934 doi: 10.5772/intechopen.89992.