Nursing Care in the Noncultured Melanocyte - Keratinocyte Surgery of Vitiligo

Main Article Content

Phantipa Treethummakul
Narumol Silpa-archa
Punyanut Yothachai
Poramin Patthamalai

Abstract

Vitiligo is a common depigmenting skin disorder, which is now clearly classified as an autoimmune disease. The disease is characterized by the selective loss of melanocytes which result in topical non-scaly, chalky-white macules in various position on the body. Vitiligo is often dismissed as a cosmetic problem and psychologically, often with a considerable burden on daily life. There are currently several medical treatments available, which aim to arrest progression and induce skin repigmentation, and no known treatment can consistently produce repigmentation in all patients. Surgical treatments for vitiligo are a safe and effective treatment modality for select patients with vitiligo. Many techniques of vitiligo surgery exist, each with unique advantages and disadvantages. This review summarize the current knowledge on vitiligo and presented the medical treatment available for vitiligo by melanocyte – keratinocyte transplantation procedure (MKTP), which is a cellular grafting consists of non-culture epidermal suspension. Nurse play a crucial role in providing effective care for vitiligo patients undergoing MKTP. The content covers is steps for surgery as for the nursing process consists of steps to pre-surgery, during surgery, and post-surgery by emphasizing the patient as the center point in providing nursing care. It presented of guidelines for the nursing of vitiligo and who interested in applying it to care for patients with vitiligo. Should be develop strategies to provide an effective educational for patients with vitiligo to enhance their quality of life.

Article Details

How to Cite
1.
Treethummakul P, Silpa-archa N, Yothachai P, Patthamalai P. Nursing Care in the Noncultured Melanocyte - Keratinocyte Surgery of Vitiligo. Siriraj Med Bull [Internet]. 2024 Oct. 1 [cited 2024 Dec. 22];17(4):318-24. Available from: https://he02.tci-thaijo.org/index.php/simedbull/article/view/267496
Section
Review Article

References

Rezaei N., Gavalas N., Weetman A., Kemp E. Autoimmunity as an aetiological factor in vitiligo. J. Eur. Acad. Dermatol. Venereol. 2007;21:865–876.

Speeckaert R, van Geel N. Vitiligo: an update on pathophysiology and treatment options. Am J Clin Dermatol. 2017; 18:733–44. 10.1007/s40257-017-0298-5.

งานเวชระเบียน โรงพยาบาลศิริราช. สถิติผู้ป่วยนอก หน่วยตรวจโรคผิวหนัง ปี พ.ศ. 2565. โรงพยาบาลศิริราช. กรุงเทพฯ: 2567.

Taïeb A, Picardo M. The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force. Pigment Cell Res. 2007;20:27–35.

Helalat M., Rawashdeh B., Odiebat H., Smadi R., Zyod I. Punch Minigrafting for Stable Vitiligo: Our Experience at the Jordanian Royal Medical Services. J. R. Med. Serv. 2012;19:81–86.

Nahhas AF, Mohammad TF, Hamzavi IH, Vitiligo Surgery: Shuffling Melanocytes. J Investig Dermatol Symp Proc 2017;18:634-7.

Dillon A.B., Sideris A., Hadi A., Elbuluk N. Advances in Vitiligo: An Update on Medical and Surgical Treatments. J. Clin. Aesthet. Dermatol. 2017;10:15–28.

วาสนภ วชิรมน. โรคด่างขาว.กรุงเทพฯ: สาขาวิชาโรคผิวหนัง ภาควิชาอายุรศาสตร์ คณะแพทยศาสตร์ โรงพยาบาลรามาธิบดี มหาวิทยาลัยมหิดล; 2561.

Gauthier Y, Benzekri L. Non-cultured epidermal suspension in vitiligo: from laboratory to clinic. Indian J Dermatol Venereol Leprol 2012;78:59-63.

Sahni K. Parsad D, Kanwar AJ, et al. Autologous noncultured melanocyte transplantation for stable vitiligo: can suspending autologous melanocytes in the patients' own serum improve repigenentation and patient satisfaction? Dermatol Surg 2011;37:176-82.

Mulekar SV. Long-term follow-up study of segmental and focal vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation. Arch Dermatol 2004;140:1211-5.

Silpa-Archa N, Griffith JL, Huggins RH, et al. Long-term follow-up of patients undergoing autologous noncultured melanocyte-keratinocyte transplantation for vitiligo and other leukodermas. J Am Acad Dermatol 2017;77:318-27.

Kruzik, Nancy. "Benefits of preoperative education for adult elective surgery patients." AORN J 90.3 2009:381-387.

Thakur V, Narayan VR, Vinay K, Dogra S. Surgical modalities of treatment in vitiligo. Cosmoderma 2021;1:13.

Huggins R, Henderson M.D, Mulekar S.V, Ozog D.M.Kerr H.A, Jabobsen G, et al. Melanocyte-keratinocyte transplantation procedure in the treatment of vitiligo: the experience of an academic medical center in the United States. J Am Acad Dermatol. 2012;66:785-93.

Mulekar S.Melanocyte-keratinocyte cell transplantation for stable vitiligo.Int J Dermatol. 2003;42:132-36.

Zhang D, Wei X, Hong W, Fu L, Qian G, Xu AE. A retrospective study of long term follow-up of 2283 vitiligo patients treated by autologous, non-cultured melanocyte-keratinocyte transplantation. Aging (Albany NY). 2021 Feb 11;13(4):5415-425.

Silpa-Archa N, Williams M.S, Lim H.W, Hamzavi I.H. Research letter: prospective comparison of recipient-site preparation with fractional carbon dioxide laser vs. dermabrasion and recipient-site dressing composition i melanocyte-keratinocyte transplantation procedure in vitiligo: a preliminary study. Br J Dermatol. 2016;174:895-97.

Nahhas, Amanda F, Mohammad, Tasneem F, Hamzavi, Iltefat H. Vitiligo Surgery: Shuffling Melanocytes. 2017;18:34-37.

Boukovalas S, Aliano KA, Phillips LG, Norbury WB. Wound healing. In: Townsend CM Jr, Beauchamp RD, Evers M, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. St Louis, MO: Elsevier, 2022: chap 6.