Drug-Resistant Situation among Tuberculosis Patients in Hatyai Hospital, Songkhla Province, Thailand

Abstract

A retrospective case –study aimed to study the drug-resistant tuberculosis situation in TB patients at Hatyai Hospital. Data were collected from patients diagnosed with all types of drug-resistant tuberculosis. In the clinic 44 tuberculosis patients registered for treatment. From 1 October 2014 to 30 September 2019 by collecting data on Medical records record treatment history Laboratory results of comorbid diseases in the electronic database system of Hat Yai Hospital and from the NTIP (National Tuberculosis Information Program) program of the Bureau of Tuberculosis. Statistical analysis was done using the frequency, percentage, mean and standard deviation. The results of the study found that TB patients treated at Hatyai Hospital There were 3,084 cases and 44 cases of drug-resistant tuberculosis were infected. The ratio of drug-resistant tuberculosis cases among men: and women were approximately 3:1, and the prevalence of drug-resistant tuberculosis patients was 30 – 44 years. Total 5 years 1.43% by drug-resistant tuberculosis infection rate from the fiscal year 2015 - 2019 classified by fiscal year The rate of drug-resistant tuberculosis infection ranged from 1.06 to 2.05 percent. Nearly all had a previous history of TB and 93.18% had been diagnosed with HIV and TB, 25.00% were enrolled as relapsed patients. (Relapse), 29.54%, drug susceptibility test found resistance to INH and Rifampicin 88.64 percent. This study shows the drug-resistant tuberculosis situation at Hatyai Hospital. The rates of drug-resistant tuberculosis infection alternately increased and decreased, with no clear trend of change. The prevalence of drug-resistant tuberculosis patients was in the age group 30 – 44 years. The prevalence of problems in this age group had a negative effect on occupation and income. The history of tuberculosis showed that almost all of them had a previous history of TB treatment. As many as one-quarter of all drug-resistant TB cases are co-infected with HIV and TB. Therefore, all HIV-infected persons must undergo TB screening and latent TB screening to ensure that they are susceptible to TB. Go into treatment and take medicine asap. In addition, a follow-up model for TB treatment should be developed. to increase the effectiveness of taking medicines in tuberculosis patients resulting in reducing the incidence of drug-resistant tuberculosis.