Neuroprotection for Intraventricular Hemorrhage Prevention in Preterm Infants


  • Chollada Chankhao Department of Maternal-Newborn Nursing and Midwifery, Srisavarindhira Thai Red Cross Institute of Nursing


neuroprotection, intravascular hemorrhage, preterm infants


Preterm infants, or babies born before 37 weeks of gestation, are at risk of intraventricular hemorrhage (IVH), particularly in those with less than 32 weeks of gestation. IVH is a major cause of mortality, cerebral palsy, and cognitive impairment among preterm infants. Factors associated with IVH include 1) the fragility of cerebral blood vessels, 2) a rapid change in cerebral blood flow due to an immature cerebral autoregulation system, and 3) lack of stabilization of blood pressure. At present, neuroprotective strategies have been applied to prevent IVH in order to decrease rapid cerebral blood flow fluctuations and cerebral ischemia. This article aims to inform and guide nurses about the pathophysiology, diagnosis, and affecting factors of IVH in preterm infants, as well as information on providing neuroprotective nursing care, including stress reduction and the prevention of hypoxia, hypothermia, and hypoglycemia, to prevent IVH in preterm infants after birth. These neuroprotective approaches could be used to improve nursing care and the quality of life of preterm infants and their families.


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