Effectiveness of Covid-19 Vaccines in Preventing Infection and Pneumonia Infection among People in a Rural District of Nakhon Si Thammarat Province
Keywords:
Effectiveness, Covid-19 Vaccines, Pneumonia InfectionAbstract
This retrospective cohort research by reviewing data from medical records aimed to study the effectiveness of the Covid-19 vaccine to prevent infection and reduce pneumonia among people in the Phrom Khiri District of Nakhon Si Thammarat Province. The samples was a population of 32,938 vaccinated people aged above 12 years, who received Covid-19 treatment services between 1 January to 30 April 2022. Study on effectiveness to prevent infection involved 5,157 people who were diagnosed with COVID-19 by ATK or RT-PCR test by hospital. Control group was 1,959 people who received negative last result from ATK or RT-PCR test by hospital, and had never been infected before. Study on effectiveness to reduce pneumonia case group was 103 patients diagnosed with pneumonia, with a control group of 5,414 patients without pneumonia, from Prom Khiri Hospital medical records data. The results of epidemiological investigations and link vaccine data from MOPH IC and Nakhon Si Thammarat Provincial Health Office. Data were analyzed with multiple logistic regression by gender, age and congenital disease variable.
Results revealed that when controlling for gender, age and congenital disease variables, people who received the vaccine against Covid-19, compared with those who haven't been vaccinated, there was no difference in infection (p value > 0.05). For the effectiveness in reducing the incidence of pneumonia, it was found that patients who got vaccinated with 3 doses reduced the chance of pneumonia by 59.6 % (AOR = 0.404, 95%CI: 0.203 - 0.806). Patients who were vaccinated with 2 doses reduced the chance of pneumonia by 49.6% (AOR = 0.504, 95%CI: 0.269 - 0.944).
Per findings, service units and public health personnel should encourage people to receive the Covid-19 vaccine at least 3 doses in order to reduce occurrence of pneumonia in when getting Covid-19 infection.
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