Primary Subcutaneous Sporotrichoid Fusarium Infection in Patient with a First HIV Diagnosis: A Case Report

Authors

  • Supakkan Nichpanit Institute of Dermatology, Department of Medical Services, Ministry of Public Health, Bangkok, Thailand
  • Oraya Kwangsukstid Institute of Dermatology, Department of Medical Services, Ministry of Public Health, Bangkok, Thailand
  • Sutsarun Prunglumpoo Institute of Dermatology, Department of Medical Services, Ministry of Public Health, Bangkok, Thailand

Keywords:

Fusarium infection, Primary subcutaneous fusarium infection, Sporotrichoid pattern, Cat related disease

Abstract

Fusarium species are responsible for various human infections, ranging from superficial to locally invasive and disseminated infections. We reported A 29-year-old Thai male with a primary subcutaneous sporotrichoid fusarium infection on his left arm and forearm, which developed after a stray cat scratch. Histopathology showed dense granulomatous infiltration in the dermis, no microorganism. Tissue culture revealed white colony. Microscopic morphology with Lactophenol cotton blue solution revealed hyaline hyphae with macroconidia. Tissue culture nucleotide BLAST sequencing revealed Fusarium solani. Hemoculture for fungus was negative. An additional assessment confirmed that the patient had HIV infection. The infection complete resolution 3 months after treatment with voriconazole.

References

References

van Diepeningen AD, Feng P, Ahmed S, Sudhadham M, Bunyaratavej S, de Hoog GS. Spectrum of Fusarium infections in tropical dermatology evidenced by multilocus sequencing typing diagnostics. Mycoses 2015;58:48-57.

Sáenz V, Alvarez-Moreno C, Pape PL, Restrepo S, Guarro J, Ramírez AMC. A One Health Perspective to Recognize Fusarium as Important in Clinical Practice. J Fungi (Basel) 2020;6:235.

Connole MD. Review of animal mycoses in Australia. Mycopathologia 1990;111:133-64.

Dignani MC, Anaissie E. Human fusariosis. Clin Microbiol Infect 2004;10:67-75.

Nucci M, Anaissie E. Fusarium infections in immunocompromised patients. Clin Microbiol Rev 2007;20:695-704.

Sugahara G, Kiuchi A, Usui R, et al. Granulomatous pododermatitis in the digits caused by Fusarium proliferatum in a cat. J Vet Med Sci 2014;76:435-8.

Bodey GP, Boktour M, Mays S, et al. Skin lesions associated with Fusarium infection. J Am Acad Dermatol 2002;47:659-66.

Watsky KL. Sporotrichoid nodules in an immunocompromised host. Cutaneous emboli of Fusarium. Arch Dermatol 1995;131:1329, 30.

Esnakula AK, Summers I, Naab TJ. Fatal disseminated fusarium infection in a human immunodeficiency virus positive patient. Case Rep Infect Dis 2013;2013:379320.

Hoenigl M, Salmanton-García J, Walsh TJ, et al. Global guideline for the diagnosis and management of rare mould infections: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology and the American Society for Microbiology. Lancet Infect Dis 2021;21:e246-e57.

Muhammed M, Anagnostou T, Desalermos A, et al. Fusarium infection: report of 26 cases and review of 97 cases from the literature. Medicine (Baltimore) 2013;92:305-16.

Maitrisathit W, Vasikasin V, Srisuttiyakorn C. Disseminated fusariosis in leukemia patient. Thai J Dermatol 2018;34:292-8.

Kantarcioglu AS, Summerbell RC, Sutton DA, et al. A dark strain in the Fusarium solani species complex isolated from primary subcutaneous sporotrichioid lesions associated with traumatic inoculation via a rose bush thorn. Med Mycol 2010;48:103-9.

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Published

2026-07-22

How to Cite

Nichpanit, S., Kwangsukstid, O. ., & Prunglumpoo , S. (2026). Primary Subcutaneous Sporotrichoid Fusarium Infection in Patient with a First HIV Diagnosis: A Case Report. Thai Journal of Dermatology, 42(3), 74–79. retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/276489

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Section

Case Report