Development of an Adverse Drug Reactions Monitoring Tool Using LINE Official Account for Antituberculous Drugs

Abstract

Background: Adverse reactions to antituberculous drugs are common. This is the cause of non-adherence and leads to drug resistance problems. A monitoring system that uses communication technology helps to find and solve problems promptly.

Objective: To develop and study a tool for monitoring adverse drug reactions from antituberculous drugs using the LINE Official Account; LINE OA.

Methods: Developmental research using the ADDIE model to develop a system was conducted as follows. 1) Analyze necessary characteristics data 2) Design a LINE OA “Tittam YaRak Pot” (version alpha) 3) Evaluate the quality by 6 experts (version beta). Take the prototype for trial in a group of 5 prototype systems (version gamma) 4) Implement the system in 15 new tuberculosis patients. 5) Evaluate efficiency and satisfaction after using the LINE OA system and reporting adverse reactions on days 3, 7, and 14. Data were analysed by descriptive statistics

Results: The developed prototype has the features of being able to chat with pharmacists immediately, 6 rich menus, and linking to google form of an adverse reaction assessment according to the schedule. Overall quality assessment results from the experts were at a good quality level, mean =4.50±0.77. From the prototype system sample were at a very good level, mean = 4.82±0.39. After implementation in new tuberculosis patients, overall satisfaction was at a very satisfy level, mean =4.44±0.56. Adverse reactions were monitored for all cases via LINE OA (86.67%). The color-changing secretions were mostly reported (35 times; 36.46%), get help ≤ 5 minutes (4 times; 40.00%), patients taking medicine continuously (30 times; 93.75%).

Conclusions: This LINE OA monitoring tool helps to find and resolve problems quickly. It can be used as a tool for adverse drug reactions monitoring.