Factors Predicting Quality of Life of Hepatocellular Carcinoma Patients Undergoing Transarterial Chemoembolisation

Authors

  • อรุณ นิลเลิศ หอผู้ป่วยผะอบฯ5(พิเศษรวม) โรงพยาบาลศิริราช เลขที่ 2 ถนนวังหลัง แขวงศิริราช เขตบางกอกน้อย กรุงเทพมหานคร
  • ผ่องศรี ศรีมรกต
  • เกศศิริ วงษ์คงคำ
  • สมราช ธรรมธรวัฒน์

Keywords:

fatigue, anorexia, insomnia, quality of life, patients with hepatocellular carcinoma, transarterial chemoembolisation

Abstract

     Objective: To study predictive correlations between fatigue, insomnia and anorexia,and the quality of life of hepatocellular carcinoma (HCC) patients during four to eight weeks after undergoing transarterial chemoembolisation (TACE).
     Design: Predictive correlational research.
     Methodology: The subjects were 77 HCC patients receiving monitoring check-ups in an out-patient ward during 4 to 8 weeks after undergoing transarterial chemoembolisation. Data were collected through a set of questionnaires: 1) a general information questionnaire; 2) the Fatigue Symptom Inventory; 3) the Insomnia Severity Index; 4) the Council on Nutrition Appetite Questionnaire; and 5) the Functional Assessment of Cancer Therapy-Hepatobiliary. The data were analysed using descriptive statistics and stepwise multiple regression analysis.
      Results: Based on the results, the participants displayed mild fatigue ( = 19.31,SD = 27.09), no insomnia ( = 6.39, SD = 7.74), moderate anorexia ( = 17.25, SD = 5.55)and good quality of life ( = 138.36, SD = 22.99). The most influential factor affecting the quality of life was fatigue (ß = -.49, p < .001), followed by anorexia (ß = -.38,p < .001) and insomnia (ß = -.18, p < .001). These three factors were capable of predicting the patients’ quality of life by up to 80% (R2 = .80, F = 96.03, p < .001).
     Recommendations: Thorough evaluation of the severity of fatigue, anorexia and insomnia in hepatocellular carcinoma patients after TACE treatment is instrumental in successfully controlling or alleviating their symptoms, or preventing such symptoms from escalating and affecting the patients’ quality of life.

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Published

2019-04-23

How to Cite

1.
นิลเลิศ อ, ศรีมรกต ผ, วงษ์คงคำ เ, ธรรมธรวัฒน์ ส. Factors Predicting Quality of Life of Hepatocellular Carcinoma Patients Undergoing Transarterial Chemoembolisation. J Thai Nurse midwife Counc [Internet]. 2019 Apr. 23 [cited 2024 Oct. 12];34(2):127-40. Available from: https://he02.tci-thaijo.org/index.php/TJONC/article/view/160724