Effects of THC on Appetite, CD4 and HIV Viral Load in People Living with HIV/AIDS
DOI:
https://doi.org/10.14456/taj.2023.5Keywords:
cannabis, THC extract, people living with HIV/AIDS, CD4, HIV viral loadAbstract
This study aimed to review the use of cannabis as a treatment for People Living with HIV/AIDS (PLWHA). Cannabis contains various cannabinoids, such as Tetrahydrocannabinol (THC), Cannabinol (CBN), Cannabidiol (CBD), Cannabichromme (CBC), and Cannabigerol (CBG). The active ingredient of cannabis is part of the endocannabinoids system, which is linked to central nervous system, peripheral nervous system, appetite, metabolism and immunity. An imbalance in the endocannabinoid system can result in ill-health. Cannabinoids can help to restore balance to this system. This paper reviewed the literature on THC in relation to HIV positive individuals, focusing on its effects on appetite, immune system functioning (CD4), and HIV virus levels. The results of the review indicated that Cannabis could provide benefits for PLWHA. THC extract could improve weight gain and dronabinol (a synthetic THC) could be used to treat anorexia and aid weight gain. THC could also enhance low mood conditions and increase CD4, CD8, and HIV virus levels in PLWHA.
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