Predictive Factors of Postoperative Complications in Prostate Cancer Surgery within 30 Days
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Abstract
Purpose: To determine the predictive power of comorbidities, frailty, and preoperative physical status on the postoperative complications in prostate cancer surgery within 30 days.
Design: Predictive correlational design.
Methods: The sample comprised of 152 patients with prostate cancer who underwent radical prostatectomy at a super tertiary hospital in Bangkok. Data were collected using personal and clinical case record form, the Charlson Comorbidity Index, the Thai version of the Edmonton Frailty Scale, the American Society of Anesthesiologists (ASA) physical status classification, and Clavien-Dindo Classification of Surgical Complications. Data were analyzed using descriptive statistics and binary logistic regression analysis.
Main findings: The participants’ mean age of the participants was 68.97 years (SD = 5.69). Postoperative complications within 30 days after radical prostatectomy was about 57.2%. The results demonstrated that all study factor could together explain 17.2% of the postoperative complications within 30 days after prostate cancer surgery, (Nagelkerke R2 = .172). Patients with frailty had a 4.63-fold higher likelihood of developing postoperative complications compared with non-frail patients (OR = 4.63; 95%CI [1.73, 12.37], p = .02). In contrast, comorbidities and preoperative physical status did not significantly predict postoperative complications within 30 days after prostate cancer surgery (p > .05).
Conclusion and recommendations: Frailty could predict postoperative complications within 30 days after prostate cancer surgery. Therefore, healthcare providers should assess frailty during the preoperative period to plan appropriate interventions to prevent or mitigate the severity of postoperative complications.
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