Cost Analysis of Autologous Hematopoietic Stem Cell Transplantation for Lymphoma and Myeloma
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Abstract
Background: Currently, autologous hematopoietic stem cell transplantation (HSCT) combined with high-dose chemotherapy is important for the treatment of lymphoma and myeloma.
Objective: To analyze the cost and hospital charges of autologous HSCT for lymphoma and myeloma at Naresuan University Hospital (NUH).
Methods: This was the cost descriptive study. The cost information was obtained from the primary data sources by cost data collection forms and interviews of relevant persons. Patients underwent autologous HSCT at NUH between 2009 and 2021. The charge information was collected from secondary data sources, such as the hospital database. Data was analyzed according to the treatment process 6 steps: 1) chemotherapy, 2) stem cell collection, 3) stem cell preservation, 4) high-dose chemotherapy, 5) recovery, and 6) follow-up care after the autologous HSCT. Descriptive statistics and one-way sensitivity analysis were performed.
Results: A total of 106 cases were 51 (48.11%) lymphoma patients and 55 (51.89%) myeloma patients. The cost of autologous HSCT for lymphoma and myeloma patients was ฿400,863.84 and ฿197,862.08, respectively. According to the sensitivity analysis, autologous HSCT costs ranged from ฿298,467.09 - ฿518,968.75 for lymphoma patients and ฿136,065.67 - ฿275,366.63 for myeloma patients. Medical care charges for lymphoma and myeloma were ฿359,391.74 (SD ฿143,935.92) and ฿162,763.56 (SD ฿48,649.74), respectively.
Conclusions: The cost of autologous HSCT was within the per capita budget allocation.
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