[2026-04-29] Huge Left Atrial Aneurysm With Severe Mitral Regurgitation: A Case Report

Authors

DOI:

https://doi.org/10.33165/rmj.2027.e276635

Keywords:

Huge left atrial aneurysm, Echocardiography, Computed tomography imaging, Surgical resection, Takotsubo cardiomyopathy

Abstract

Background: Huge left atrial aneurysm (LAA) is a rare cardiac anomaly that may be detected late, leading to serious complications such as systemic thromboembolism, arrhythmias, mitral regurgitation, and heart failure. Early surgical intervention is currently
the standard treatment for symptomatic cases to prevent catastrophic consequences.

Case Presentation: A 31-year-old woman presented with progressively worsening shortness of breath and intermittent palpitations, diagnosed with a huge LAA and severe mitral regurgitation. Two surgeries were undertaken: the first was LAA ligation and mitral valve repair, followed 7 days later, by complete resection due to compression complications. The patient subsequently developed severe left ventricular dysfunction but recovered well after 10 days of intra-aortic balloon pump support and intensive medical treatment.

Conclusions: This case highlights the importance of appropriate surgical techniques and therapeutic challenges in managing patients with complex LAA.

References

Fakhri G, Obeid M, El Rassi I, et al. Large congenital left atrial wall aneurysm: an updated and comprehensive review of the literature. Echocardiography. 2020;37(6):965-970. doi:10.1111/echo.14687

Grinfeld R, Trainini JC, Roncoroni A, Fabrykant F, Cacheda H, Tripodi G. Congenital aneurysm of the left atrium. Ann Thorac Surg. 1985;39(5):469-471. doi:10.1016/s0003-4975(10)61961-3

Cai Y, Wei X, Tang H, Dian K. Congenital aneurysm of the left atrial wall. J Card Surg. 2016;31(12):730-734. doi:10.1111/jocs.12866

Fry W. Herniation of the left auricle. Am J Surg. 1953;86(6):736-738. doi:10.1016/0002-9610(53)90388-2

Semans JH, Taussig HB. Congenital “aneurysmal” dilatation of the left auricle. Bull Johns Hopkins Hosp. 1938;63(6):404-414.

Daralammouri Y, Odeh A, Abuzahra S, Azamtta M, Shawahna R. Left atrial appendage aneurysm: a descriptive systematic review of 177 cases. BMC Cardiovasc Disord. 2024;24(1):633. doi:10.1186/s12872-024-04323-x

Pradella M, Mozer AB, Baraboo JJ, et al. Blood flow dynamics in a giant left atrial appendage aneurysm visualized by 4D-flow CMR. JACC Case Rep. 2021;3(18):1924-1929. doi:10.1016/j.jaccas.2021.10.009

Apostolakis E, Shuhaiber JH. The surgical management of giant left atrium. Eur J Cardiothorac Surg. 2008;33(2):182-190. doi:10.1016/j.ejcts.2007.11.003

Stone KS, Brown JW, Canal D, Caldwell R, Hurwitz R, King H. Congenital aneurysm of the left atrial wall in infancy. Ann Thorac Surg. 1990;49(3):476-478. doi:10.1016/0003-4975(90)90262-5

Wei X, Zhang X, Tang H, Dian K. A rare case of giant left atrium in a child. Eur Heart J. 2016;37(8):683. doi:10.1093/eurheartj/ehv664

Zoghbi WA, Levine RA, Flachskampf F, et al. Atrial functional mitral regurgitation. A JACC: Cardiovascular Imaging expert panel viewpoint. JACC: Cardiovasc Imaging. 2022;15(11):1870-1882. doi:10.1016/j.jcmg.2022.08.016

Bouchaala A, Nafii O, Belharty N, Mesfioui MB, Oukerraj L, Cherti M. Surgery as precipitating factor of Takotsubo cardiomyopathy, characteristics and challenges: a case series. IHJ Cardiovascular Reports. 2024;8(1):32-35. doi:10.1016/j.ihjcvr.2024.04.002

Downloads

Published

2026-04-29

How to Cite

1.
Nga NTV, Ha NH, Hue PT, Huy LQ. [2026-04-29] Huge Left Atrial Aneurysm With Severe Mitral Regurgitation: A Case Report. Res Med J [internet]. 2026 Apr. 29 [cited 2026 Apr. 30];:e276635. available from: https://he02.tci-thaijo.org/index.php/ramajournal/article/view/276635

Issue

Section

Case Reports