Comparison of Rate of Hemolysis Between Vacuum Blood Collection Tube Versus Syringe Method

Abstract

Hemolysis leads to error laboratory report and more difficult treatment decision. So treatment is delayed and mortality increase. The use of vacuum blood collection tube may increase hemolysis.
Objective: To compared rate of hemolysis between vacuum tube and syringe blood collection. Method: We enrolled patients who presented at emergency department of Ratchaburi Hospital between February 1, 2014 and April 30, 2014. The subjects were randomized into 2 groups, group of vacuum blood collection tube or group of syringe. Hemolysis rate was collected and analyzed between both groups
Results: During study period, 300 patients were enrolled. Rate of hemolysis increased in significantly Vacuum blood collection tube group than syringe group. (6.70 vs 0.70 p-value = 0.006) odds ratio 10.64 (95%CI = 10.64-84.21) In vacuum blood collection tube group, using intravenous catheter had more hemolysis rate, but without statistic significance, than straight needle. (p-value = 0.063) Conclusions: Vacuum blood collection tube was increase hemolysis in blood sample significantly than syringe.