การศึกษาโรคตับอ่อนอักเสบเฉียบพลันและปัจจัยพยากรณ์ความรุนแรง ที่โรงพยาบาลนครปฐม

บทคัดย่อ

Objective : To study clinical data, predictive factors, management and treatment results in patients presented with acute pancreatitis.

Materials and Methods : Retrospective study were done by reviewing medical record of patients presented with acute pancreatitis at Nakhonpathom Hospital since January 2007- November 2009. Clinical and laboratory features at first date of admission were assessed to look for predictive factors in severity of acute pancreatitis.

Result : Overall patients in this study were 127 (male 90, female 37). 91 patients (71.7%) had mild disease whereas 36 (28.3%) had severe. Applicable laboratory predictive factors were serum albumin at cutoff level < 3.7 g/dl and serum calcium at cut-off level < 8.1 mg/dl. Sensitivity in predictability of serum abumin and calcium were 67% and 58% and specificity were 61% and 90%, respectively. Use combination of both factors can increase sensitivity and specificity to 73% and 100%, respectively.

Conclusions : Serum albumin and serum calcium level at first date of admission can be used in predict severity of acute pancreatitis.