ภาวะตัวเหลืองในทารกแรกเกิด โรงพยาบาลนครปฐม

บทคัดย่อ

     Prospective study of incidence, risks and causes of neonatal jaundice in Nakhonpathom hospital was done in 2,710 newborns, from 15 November, 2006 to 31 May, 2007. There were 391 newborns with neonatal jaundice (14.4%). They were 308 full term (78.7%), 83 preterm (21.2%). Another 33 newborns with neonatal jaundice were referred from other hospital. Totally the study was performed in 424 newborns.

     In 15 newborns (3.5%), jaundice occurred in first 24 hours, in 81 newborns (19.1%) occurred between 24-48 hours, in 175 newborns (41.3%) occurred between 49-72 hours and in 153 newborns (36.1%) occurred more than 72 hours. The average age was 54.86 hours, microbilirubin level was 4.3 mg/dl in minimum and 43.9 mg/dl in maximum. About feeding, there were 304 newborns (71.7%) that took only breast feeding, 80 newborns (18.9%) took breast feeding and cow milk, 24 newborns (5.7%) took only cow milk and 16 newborns (3.8%) were ordered to NPO. Etiology of jaundice were breast feeding jaundice, jaundice unspecified and G6PD deficiency respectively. Newborns that had highest average level of microbilirubin were breast milk jaundice, then ABO incompatibility with G6PD deficiency and breast feeding jaundice respectively. In early developed jaundice group, they were ABO incompatibility with G6PD deficiency, then premature and birth asphyxia babies respectively. About the phototherapy, the longest duration of therapy was in birth asphyxia, sepsis and enclosed hemorrhage respectively. All cases were treated by appropiate feeding plus phototherapy. Exchange transfusion was done one case. After treatment, all cases had no complication. The result of the study show about etiology, preventive method and the appropriated treatment of neonatal jaundice.