ความคงตัวของผลิตภัณฑ์ยาฉีดเข้ากล้ามเนื้อ Celtriaxone

บทคัดย่อ

Stability of three brands of 1 g ceftriaxone intramuscular injections were studied. The powdered drug of all brands were first dissolved in water for injection and analyzed for celtriaxone .  contents. The solutions were separately kept at 4° C and 30° C and they were withdrawn to analyzed every week. Results indicated that the three brands of 1 g ceftriaxone intramuscular injections were pharmaceutical equivalence. Reconstituted products of all brands were stable for one week when refrigerated at 4° C, while at 30°C they were not. Brand ll was the least stable product.