ปัจจัยเสี่ยงต่อการเสียชีวิตของทารกที่มีภาวะสูดสำลักขี้เทาในโรงพยาลประจวบคีรีขันธ์

บทคัดย่อ

A retrospective study was done to identify antenatal and intrapartum risk factors which may be preventable. There were 59 infants who had meconium stained amniotic fluid and developed respiratory distress during October 1^st, 1996 to September 30^th, 1999 in Prachuapkhirikhan Hospital. Meconium Aspiration Syndrome occurred in 1.11% of total birth or 15.45% of meconium stained amniotic fluid. Data were analyzed by Chi-Square test, Odds Ratio and Logistic regression analysis. The results revealed that risk factors significantly associated with neonatal death on Meconium Aspiration Syndrome were no direct intratracheal suction (p = 0.01, OR = 4.95), 5 minutes Apgar < 7 (p = 0.03, OR = 4.07), 1 minute Apgar < 7 (p = 0.05, OR = 3.83). Logistic regression analysis identified only three variables, statistically significant effect on neonatal death on Meconium Aspiration Syndrome were no direct intratracheal suction (OR = 55.0393), 5 minutes Apgar < 7 (OR = 10.8118) and gestational age > 42 weeks (OR = 10.0005). Clinical sepsis was the commonest complication followed by pneumonia, persistent pulmonary hypertension of the newborn (PPHN) and pneumo- thorax. PPHN was the most serious complication.