การศึกษาเปรียบเทียบฤิทธิ์การขยายหลอดลมของยาซัลบิวตามอลผ่านเบบี้เฮเลอร์ และขวดน้ำดื่มที่ดัดแปลงเป็นท่อต่อ

บทคัดย่อ

The aim of the study was to compare bronchodilator response of salbutamol sulphate 200 micrograms when administered via an MDI with Babyhaler in conjunction with MDI and the applied  Drinking-water spacer. By experimental study, sixty pediatric asthmatic patients with spontaneous episode of acute asthmatic attack divided into two groups. The patients inhaled salbutamol sulphate at the dosage of 200 micrograms from either the Babyhaler or the applied Drinking-water spacer. Using Miniwright peak flow meter to measure peak expiratory flow rate (PEFR) and evaluate Wood’s clinical asthma score of the patients before and after inhaled salbutamol sulphate at 5, 20, 60 minutes. Both groups results in an increased in PEFR and decreased in Wood’s clinical asthma scores without any statistical difference from 5 to 60 minutes. For pediatric asthmatic patients with difficulty in coordinating to an MDI and for economic reasons, the applied Drinking-water spacer proved to be a safe and efficient delivery system which is considerably to be another wayto try.