ความชุกของธาลัสซีเมีย และฮีโมโกลบิน ผิดปกติในจังหวัดนครนายก

บทคัดย่อ

          The prevalence of Thalassemia and Hemoglobinopathy in Nakhonnayok province was surveyed during January 1989 to December 1991. The 1,765 samples were tested by hemoglobin electrophoresis on cellulose acetate in tris-EDTA buffer pH 8.6. It was found that 24.7% were heterozygous E, 2.4% were Homozygous E, 2.2% were HbH, 2.4% were β^o -thalassemia/ HbE, 0.4% were β^o -thalas-semia/HbE and 8.9% were β-thalassemia trait. These data indicated high prevalence of Thalassemia and Hemoglobinopathy in Nakhonnayok population. Other studies in Thailand were reviewed and innovative strategies for prevention and control were suggested.