สครับ ทัยฟัส ในยุทธการนเรศวร : การศึกษาในผู้ป่วย 34 ราย

บทคัดย่อ

          A descriptive analytic clinical study was carried out during September 1, 1992 to February 28, 1993 at Hua-Hin Hospital in corporation with the Bangkok hospital for Tropical Diseases, Mahidol University to evaluate the outcome of scrub typhus from Naresuan strategy in 34 cases of border patrol policemen during on the action at Bang-Kloy village, Kangkachan district, Petchburi Province.

          It was found that the commonest clinical findings were fever, chill, headache, myalgia. Eschar were found in 35.3%. Most of them were at the upper part of the body. Lymphadenopathy mostly were localized but generalized. form was also found. The laboratory findings were not striking except lymphocytosis. In this study Weil-Felix agglutination test to OXK was found to be positive at a titre of 1 : 160 or over in 58.8% but a confirmation test with Indirect lmmunoperoxidase test yielded a hundred percent positive for IgM titre of 1 :400 or more but IgG titre of 1 :1600 or over was only 52.9%.

          Five patients had complication which were jaundice, ascites, adult respiratory distress syndrome and encephalopathy. Patients were treated with doxycycline 200 mg once daily for 3 consecutive days. They all responded well. No dead occurred in this group of patients.