The Outcome of Management in Sepsis and Septic Shock Patient Who Admitted to an Emergency Department at Jainad Narendra Hospital: 6-Months Retrospective Observational Cohort Study
Main Article Content
Abstract
Sepsis and septic shock are life-threatening conditions and a major public health problem worldwide. This retrospective cohort study aimed to study the outcomes of management for patients with sepsis and septic shock in the emergency department (ED) at Jainad Narendra Hospital. The sample consisted of 227 patients with sepsis and septic shock who received care in the ED. They were selected using a purposive sampling method. The research instruments were the data recording form, including the personal information and treatment received, and the management outcomes form. Data were analyzed using descriptive statistics and the Wilcoxon signed-rank test. The research findings revealed that the average time from patient arrival at the ED to diagnosis was significantly longer than the established criteria of 15 minutes at the .05 significance level (mean=27.06, SD=35.95, median=15.00), while the average time from diagnosis to the administration of antibiotics was significantly different from the established criteria of 60 minutes at the .05 significance level (mean=32.79, SD=28.17, median=25.00). Additionally, 74.01% of the patients received intravenous fluid within 3 hours, 7.49% received vasopressor medication, and 72.20% were treated in the ED within 2 hours. These measures contributed to a survival rate of 79.70%. The findings of this study indicate that certain aspects of the care process for patients with infections and septic shock in the emergency department may still require improvement, such as the screening and initial assessment, in order to facilitate faster diagnosis and treatment. Such improvements could help increase the survival rate of patients.
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
บทความและรายงานวิจัยในวารสารพยาบาลกระทรวงสาธารณสุข เป็นความคิดเห็นของ ผู้เขียน มิใช่ของคณะผู้จัดทำ และมิใช่ความรับผิดชอบของสมาคมศิษย์เก่าพยาบาลกระทรวงสาธารณสุข ซึ่งสามารถนำไปอ้างอิงได้
References
La Via L, Sangiorgio G, Stefani S, Marino A, Nunnari G, Cocuzza S, et al. The global burden of sepsis and septic shock. Epidemiologia 2024;5(3):456-78. doi:10.3390/epidemiologia5030032
Mellhammar L, Wollter E, Dahlberg J, Donovan B, Olséen CJ, Wiking PO, et al. Estimating sepsis incidence using administrative data and clinical medical record review. JAMA Netw Open 2023;6(8):e2331168. doi:10.1001/jamanetworkopen.2023.31168
Health Data Center. Health Data Center (HDC) in Thailand; 2024. Received from https://itjournal.moph.go.th/page/detail/22
Font MD, Thyagarajan B, Khanna AK. Sepsis and septic shock - Basics of diagnosis, pathophysiology and clinical decision making. Med Clin North Am 2020;104(4):573-85. doi:10.1016/j.mcna.2020.02.011
Kamath S, Hammad Altaq H, Abdo T. Management of sepsis and septic shock: what have we learned in the last two decades?. Microorganisms 2023;11(9):2231. doi:10.3390/microorganisms11092231
Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 2016;315(8):801-10. doi:10.1001/jama.2016.0287
Jamroenwong N, Piyarak S, Chaiwong C. Assessment and nursing care of a patient with septic shock. The Southern College Network Journal of Nursing and Public Health 2020;7(1):319-30. (in Thai)
Sriwilai W. Emergency nursing care for patients with septic shock. Journal of The Police Nurses and Health Science 2024;16(1):237-49. (in Thai)
Dugar S, Choudhary C, Duggal A. Sepsis and septic shock: guideline-based management. Cleve Clin J Med 2020;87(1):53-64. doi:10.3949/ccjm.87a.18143
Gavelli F, Castello LM, Avanzi GC. Management of sepsis and septic shock in the emergency department. Intern Emerg Med 2021;16(6):1649-61. doi:10.1007/s11739-021-02735-7
Kuntorn N, Wangsrikhun S, Yothayai C. Development of a Multidisciplinary Sepsis Management Model in an Emergency Department. Nursing Journal CMU 2024;51(3):68–83. (in Thai)
Im Y, Kang D, Ko RE, Lee YJ, Lim SY, Park S, et al. Time-to-antibiotics and clinical outcomes in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study. Crit Care 2022;26(1):19. doi:10.1186/s13054-021-03883-0
Waranung T. Outcomes of using the clinical practice guideline for patients with sepsis at fang hospital, Chiangmai Province. Chiangrai Medical Journal 2019;11(1):1-8. (in Thai)
Jindakul C, Yoiepho C. Development of care system for sepsis patients in Emergency room, Phayakkhaphumphisai Hospital, Mahasarakham Province. Academic Journal of Mahasarakham Provincial Public Health Office 2024;8(15):92-107. (in Thai)
Donabedian A. An introduction to quality assurance in health care. New York, NY: Oxford University Press; 2003.
Sangkittipiboon N, Sa-nganate A, Tabudda P. Study on the quality of care management for patients with bloodstream infection symptoms at the inpatient nursing unit, Lopburi Cancer Hospital. Journal of Environmental and Community Health 2024;9(4):196–204. (in Thai)
Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med 2021;47(11):1181-247. doi:10.1007/s00134-021-06506-y
Samanchai Y. Results of care for septic patients between older and new doctors Wapipatum hospital, 2018. The Office of Disease Prevention and Control 10th Journal 2019;17(1):32–42. (in Thai)
Techa-atik P, Sumritrin S, Sirithongsuk A, Poogeng P. Delaying time periods of the service for accident and emergency patients. Thai Journal of Nursing and Midwifery Practice 2017;4(1):25-35. (in Thai)
Locker TE, Mason SM. Analysis of the distribution of time that patients spend in emergency departments. BMJ. 2005;330(7501):1188-9. doi:10.1136/bmj.38440.588449.AE
Pramungkata W. Development of Guideline Model for Sepsis patients at Srisomdet Hospital. Journal of Research and Health Innovative Development 2024;5(1):603–623. (in Thai)