Efficacy and safety of Hyptis suaveolens extract in HIV-infected individuals: A preliminary study
Keywords:
สารสกัดสมุนไพรแมงลักคา, ผู้ติดเชื้อเอชไอวีAbstract
A clinical study was conducted to study preliminary efficacy and side effects of water extract of Hyptis suaveolens (L.) Poit in HIV-infected individuals at Mae-Sai Hospital, Chiang Rai province. Twenty-six HIV-infected asymptomatic persons with CD4+ cells greater than 250 cell/mm3 received two capsules of 250 mg H. suaveolens extract orally three times a day for 6 months. The results showed no significant changes in the number of CD4+ cells and HIV viral load. Significant decrease in Hemoglobin and albumin was observed but within normal limits in months 6 and 3, respectively, of the treatment. Changes in other hematological and biochemical parameters were not found throughout the study. No subjects experienced side effects from the treatment. The study suggested that the water extract of H. suaveolens at the dose of 1,500 mg/day orally given to HIV-infected individuals for 6 months was safe and the patients reported their satisfaction from the treatment.
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