Comparison study of vocal cord conditions for intubation between cisatracurium 0.1 mg/kg together with sevoflurane and cisatracurium 0.15 mg/kg in patient undergoing abdominal hysterectomy
Keywords:
cisatracurium, sevoflurane, vocal cords coditions, intubationAbstract
Objective : To compare the conditions of vocal cords for endotracheal intubation by using cisatracurium 0.10 mg/kg together with sevoflurane compared to those by using cisatracurium 0.15 mg/kg in patients undergoing abdominal hysterectomy.
Methods : The study method was a double-blinded randomize control trial . A total of 184 patients were randomly divided into two groups and received medication with midazolam and fentanyl , then anesthesia was induced by propofol. Group study ( S group) received cisatracurium 0.10 mg/kg and then control ventilation via face mask with O2:N2O 2:4 liters/minutes, plus 4% sevoflurane for 3 minutes. Group control (C group) received cisatracurium 0.15 milligrams/kg and control ventilation via face mask with O2:N20 2:4 liters/minutes for 3 minutes, then started the intubation and evaluated the quality of the vocal cords ,intubation, the Vital signs and the complications during and after the intubation.
Result : The result showed that There were no statistically significant differences in the vocal cord condition from both groups (group S opened at 92.39% ,group C 96.74% P value =0.193)
Group S ‘s the average of blood pressure was statistically significant lower than Group C both before intubation ( p-value= 0.007, 95% CI= 1.39,8.44) and after immediately intubation (p-value= <0.001, 95% CI=4.50,15.71) quality and complications of intubation were not different.
Conclusion : The use of sevoflurane can enhance the effect of cisatracurium 0.1mg/kg. in intubation as well as using cisatracurium 0.15 mg/kg.
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