Treatment outcome and associated factors of rectal cancer in Roi-Et hospital.

Authors

  • สุขนิตย์ พรหมรับ

Keywords:

Rectal cancer, Treatment outcome, Associated factors, Roi-Et hospital

Abstract

Objective : To study treatment outcome and associated factors of rectal cancer in Roi-Et hospital.

Method : This study is analytic study by retrospective data collection. The medical record and pathological report are reviewed in patients who were diagnosed as rectal cancer between Jan 2011 to Dec 2021.

Result : This study shows Serum CEA more than 2.5 ng/dL, Post op CMT,Post-op CCRT, Tumor grade, Stage, Resection margin are associated statistically significant with overall survival. In addition, disease free survival is associated statistically significant with serum CEA more than 2.5 ng/dL, Pre-op CCRT, Post-op CCRT, Post-op CMT, Surgery, Tumor grade, T stage,  Resection margin. 2 year survival is 76.0% and 5 years survival is 13.0%.

Conclusion : The treatment outcome of rectal cancer in Roi–Et hospital is in international standard. The associated factors that associate to overall survival and disease free survival should be considered for the treatment choice for better outcome of rectal cancer patients in Roi-Et hospital.

References

Kanokphan Phansranoi, Supot Kamsa-ard, Nut Boonnithi, Nintita Sripaiboonkij Thokanit, Naowarat Maneenin. ไส้ตรงหลังการวินิจฉัยที่ได้รับการรักษาในโรงพยาบาลมหาราช นครราชสีมา จังหวัดนครราชสีมา. Srinagarind Med J. 2021 Apr 7;36(2):222–8.

Juan A. Díaz-González, Felipe A. Calvo, Javier Cortés, José L. García-Sabrido, Marina Gómez-Espí, Emilio Del Valle, et al. Prognostic factors for disease-free survival in patients with T3-4 or N+ rectal cancer treated with preoperative chemoradiation therapy, surgery, and intraoperative irradiation. Int J Radiat Oncol Biol Phys. 2006 Mar 15;64(4):1122–8.

Jean-François Bosset, Laurence Collette, Gilles Calais, Laurent Mineur, Philippe Maingon, Ljiljana Radosevic-Jelic, et al. Chemotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med. 2006 Sep 14;355(11):1114–23.

รัชนก สิทธิโชติวงศ์. ผลลัพธ์ทางคลินิกในผู้ป่วยโรคมะเร็งลำไส้ระยะลุกลาม หรือกลับเป็นซ้ำที่รักษาด้วยยาเคมีบำบัด. วารสารการแพทย์โรงพยาบาลศรีสะเกษ สุรินทร์ บุรีรัมย์. 2009;24(1):139–49

Jose G. Guillem, David B. Chessin, Alfred M. Cohen, Jinru Shia, Madhu Mazumdar, Warren Enker, et al. Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer. Ann Surg. 2005 May;241(5):829–36; discussion 836-838.

van Zoggel DMGI, Bosman SJ, Kusters M, Nieuwenhuijzen G a. P, Cnossen JS, Creemers GJ, et al. Preliminary results of a cohort study of induction chemotherapy-based treatment for locally recurrent rectal cancer. Br J Surg. 2018 Mar;105(4):447–52.

ภานุวัฒน์ ขันธสะอาด. โรคมะเร็งลำไส้ใหญ่ในโรงพยาบาลมหาสารคาม. วารสารโรงพยาบาล มหาสารคาม. 2015;12(2):101–11.

Gerard J-P, Chapet O, Nemoz C, Hartweig J, Romestaing P, Coquard R, et al. Improved sphincter preservation in low rectal cancer with high-dose preoperative radiotherapy: the lyon R96-02 randomized trial. J Clin Oncol Off J Am Soc Clin Oncol. 2004 Jun 15;22(12):2404–9.

Prangrawee Sangchan. Outcomes of preoperative radiotherapy in rectal cancer: a single institute experience. J Thai Assoc Radiat Oncol. 2021 Jun 18;27(1):R67–80.

Downloads

Published

2022-08-29

How to Cite

พรหมรับ ส. . (2022). Treatment outcome and associated factors of rectal cancer in Roi-Et hospital. Mahasarakham Hospital Journal, 19(2), 186–196. retrieved from https://he02.tci-thaijo.org/index.php/MKHJ/article/view/258056

Issue

Section

Articles