Once weekly oral doses of Generic Fluconazole 200 mg in the treatment of Tinea corporis and Tinea cruris: A preliminary report

Authors

  • Oraparn Techaritpitak DEPARTMENT OF DERMATOLOGY, MEDICINE, BURAPHA UNIVERSITY, CHONBURI, THAILAND
  • Manotham Usaho DEPARTMENT OF DERMATOLOGY, MEDICINE, BURAPHA UNIVERSITY, CHONBURI, THAILAND
  • Anita Kruavit DEPARTMENT OF DERMATOLOGY, MEDICINE, BURAPHA UNIVERSITY, CHONBURI, THAILAND
  • Sirinant Nakwan DEPARTMENT OF DERMATOLOGY, MEDICINE, BURAPHA UNIVERSITY, CHONBURI, THAILAND
  • Natta Rajatanavin DEPARTMENT OF DERMATOLOGY, MEDICINE, BURAPHA UNIVERSITY, CHONBURI, THAILAND

Keywords:

Fluconazole, once-weekly, tinea corporis, tinea cruris

Abstract

Background : Tinea corporis and Tinea cruris are common superficial fungal infections caused by dermatophytes.A number of topical antifungal preparations are available for the treatment of superficial dermatophytosis.  However,  in the case of widespread and  multiple sites of infection, the topical application is considered unsatisfactory. Fluconazole is active in vitro against common pathogen of Tinea corporis and Tinea cruris, and is clinically effective in the treatment of a wide variety of superficial fungal infection. 

Objective : To evaluate efficacy of oral once weekly dose of generic Fluconazole 200mg over 6 weeks.

Methods : An open, noncomparative study, Tinea corporis and Tinea cruris patients were treated with generic Fluconazole 200mg once weekly for 6 weeks. Clinical and mycologic assessments were performed before treatment, at the end of treatment and at 4 weeks after treatment. All adverse events were recorded.

Result : Furetn patients were diagnosed as dermatophyte infection, 15/20 had cistve. After 6 week of treatment, both KOH and fungal culture were negative in twelve patient (80% efficacy). No patients experienced adverse events.

Conclusion : In this report Fluconazole 200mg once weekly for 6 weeks is effective and safe regimen in the treatment of Tinea corporis and Tinea cruris.

References

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Published

2026-07-03

How to Cite

Techaritpitak, O., Usaho, M., Kruavit, A., Nakwan, S., & Rajatanavin, N. (2026). Once weekly oral doses of Generic Fluconazole 200 mg in the treatment of Tinea corporis and Tinea cruris: A preliminary report. Thai Journal of Dermatology, 23(2), 93–101. retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/283417

Issue

Vol. 23 No. 2 (2007): April-June

Section

Original articles

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Copyright (c) 2007 Thai Journal of Dermatology

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ

บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น