Glycemic Index and Randomized Study Comparing the Responses of Glucose, Insulin and Lipid Profiles in Blood of NOVICAL-DM with Diabetes-specific Nutrition Formula (Glucerna SR® Triple Care) in Type 2 Diabetic Patients
Abstract
As the prevalence of type 2 diabetes increases steadily, controlling blood glucose before and after
consumption is important for patients. The research team developed NOVICAL-DM as a diabetes-specific
nutrition formula, or medical food with a low glycemic index (GI). This research was a randomized, crossover study which aimed to study the glycemic index of NOVICAL-DM in 12 healthy volunteers using a glucose solution as a reference and to study the responses of blood glucose, insulin and lipid profiles in 14 type 2 diabetic patients after consuming NOVICAL-DM compared with Glucerna (Glucerna SR® triple care, GI = 41). The results showed that NOVICAL-DM had a low glycemic index of 19 and showed that type 2 diabetic patients had mean levels of blood glucose, insulin and lipid profiles after consuming NOVICAL-DM and Glucerna. However, NOVICAL-DM had mean value of incremental area under the curve of blood glucose over 240 minutes significantly lower than that of Glucerna, which was 32% lower (4,398 vs 6,508 mg x min/dL, p < 0.05). This study indicated that the consumption of NOVICAL-DM with low GI (= 19) was more beneficial for controlling postprandial blood glucose in type 2 diabetic patients than Glucerna SR® triple care.
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