Stability Study for Methamphetamine Standard Solutions

Abstract

       Methamphetamine is a major drugs problem in the country. The spread of this drug and severity of the problem is continuing. One approach to control and reduce the spread of the drug is arrest and analysis of drug for further legal action. The analysis of drugs requires standard substance which is expensive and difficult supply. The aim of this study is to establish the shelf life of the methamphetamine standard solution prepared in BDN laboratory. The stability of methamphetamine standard solution was investigated by using a routine gas chromatographic technique, The quantitative detection of methamphetamine for illicit sample was performed in the duration of 128 days. Both methamphetamine standard solutions with the concentration about 0.4 milligrams per milliliter chloroform prepared and stored at 2-8 degree centigrade and the freshly prepared methamphetamine standard solution, were used for determination of methamphetamine content of illicit sample. At the end of the study periods, the percentage by weight different of two methamphetamine standard solution used was in the range of 0.11 – 1.96. This result showed that the expiry date of the methamphetamine standard solution was 128 days without any remarkable degradation. Therefore, all of illicit standard solutions should be studied for their expiry date to support the analysis of drug for the illicit drug control and legal action.