Health Risk of Laboratory’s Staffs of Regional Medical Sciences Center 3, Nakhon Sawan in Using of Hazardous

Abstract

       Factor effecting to Thai people health have been realized as environment contaminated with chemicals and more carcinogens. In 2012, a study of health risks of of laboratory’s staffs using of hazardous chemicals in the laboratory of Regional Medical Sciences Center 3 Nakhon Sawan were performed in order to protect and monitor the health of the staffs. Blood samples were from 37 staffs which are divided into two groups i.e. 20 persons (54%) of exposing to hazardous chemicals in the laboratory and the other group of 17 persons (46%) not exposing to hazardous chemicals in laboratory. Check for all items of Complete Blood Count (CBC) of both groups blood samples showed the results which are within the normal range. The average frequency of micronucleus from white blood cells of the staffs not exposed to hazardous chemicals in laboratories were higher than those of the staffs exposed to hazardous chemicals in the laboratory, which significant difference (p <0.05) form each other i.e. (mean ± SD) were 2.47 ± 1.56 cell/1000 BN cell and. 1.35 ± 1.87 cell/1000 BN cell, respectively, However, the average frequency of micronucleus from white blood cells of both group were within the normal range, i.e. normal cell should have the average frequency of micronucleus in the range of 0-5 cell/1000 BN cell. High average frequency of micronucleus from white blood cells of the staffs not exposed to hazardous chemicals may be due to other factors, such as indirect exposure to chemicals, toxic surfactant or carcinogens, drinking alcohol, smoking, exposure to lead paint from hereditary or exposure to radiation from x-ray which are toxic to the cells. Results form the study could enable staffs to take care and protect themselves from exposure to toxic substances, both directly and indirectly. The authorities should to conduct ongoing surveillance. In the future, it is likely to take the micronucleus frequency as a parameter as well as the integrity of the blood (Complete Blood Count: CBC) to monitor cancer (Cancer Risk Biomarker).