Chest Radiographic Findings of Multidrug-resistant Pulmonary Tuberculosis in Comparisons to Drug-sensitive Pulmonary Tuberculosis in Non-HIV Patient
Keywords:
chest radiograph, pulmonary tuberculosis, multidrug-resistantAbstract
Objectives : The study aims to describe the characteristics of chest radiography imagings in drug-sensitive pulmonary tuberculosis (DS-TB) and multidrug-resistant pulmonary tuberculosis (MDR-TB) and to identify potential characteristics indicating MDR-TB in non-AIDS patient.
Method : All patients with sputum positive TB registered at Samutsakhon Hospital since January to December 2013 were collected. Patients’ medical data were recorded and all chest radiographic imagings were reviewed and statistic analysis.
Results : Among 151 patients included in the study, 130 patients were identified DS-TB and 21 patients were MDR-TB. Of 130 DS-TB patients, 73 were male and 57 were female. Mean age was 38 years (18-82 years). For MDR-TB, 14 and 7 patients were male and female respectively. Mean age was 43 years (21-78 years). Single lobar cavity (41.5%), multilobar reticulonodular infiltration (36.2%), single lobar consolidation (31.5%) and single lobar reticulonodular infiltration (31.5%) were common in DS-TB while multilobar reticulonodular infiltration (47.6%), multilobar consolidations (42.8%), multiple cavities (38%) and multiple bronchiectasis (23.8%) were common in MDR-TB. However, multilobar consolidations (p=0.001), multiple cavities (p =0.025), multiple bronchiectasis (p=0.009), combined multilobar consolidation and multiple bronchiectasis (p=0.000) were statisticcal significant to indicate MDR-TB.
Conclusion : Multilobar consolidations, multiple cavities and multiple bronchiectasis were potential chest radiographic imaging findings for drug resistant pulmonary tuberculosis with sensitivity and specificity were 82% and 69%, 75% and 75%, 57% and 83% respectively.
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ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์
