Early Detection of Prostate Cancer Using Serum PSA Level and/or Digital Rectal Examination in Chaoprayayomrat Hospital, Suphanburi

Abstract

Objective of this study was to determine the significant level of serum prostatic specific antigen (PSA) and digital rectal examination (DRE) findings, which indicate high risk of prostate cancer in Chaoprayayomraj Hospital, Suphanburi. Retrospective review shows that from October 2005 to September 2008, 45 male patients who had positive serum PSA level and abnormal or normal DRE findings were performed biopsy of prostate gland. The statistically significant level of PSA for prostate cancer detection is at > 20 ng/ml (p value < 0.01). Prostate cancer was found in patients who had abnormal DRE finding, that was statistically significant (p value = 0.004). This study confirms that serum PSA level > 20 ng/ml and/or abnormal DRE finding indicate high risk of prostate cancer significantly. So prostate biopsy should be performed in the patients who have serum PSA level > 20 ng/ml and/or abnormal DRE finding for early detection of prostate cancer.