Effect of Cream Bases of Turmeric Cream on Antimicrobial Activity

Authors

  • Saranya Tharaswaeng Medicine Plant Research Institute, Department of Medicine Science of Public Health
  • Ratchanee Tipsombat Medicine Plant Research Institute, Department of Medicine Science of Public Health
  • Pattamawadee Setakanna Medicine Plant Research Institute, Department of Medicine Science of Public Health
  • Ratchanee Tipsombat Medicine Plant Research Institute, Department of Medicine Science of Public Health
  • Jiranuch Mingmuang Medicine Plant Research Institute, Department of Medicine Science of Public Health

Keywords:

Curcuma longa, turmeric, cream base, antimicrobial activity

Abstract

          Ethanolic extract of Turmeric was incorporated in 5 cream bases at 2 concentrations of 0.2% and 1.0%. by weight. The 5 cream bases were anionic and nonionic from British Pharmacopoeia (B.P) and National Formulary of Essential Drug of Thailand (E.D.) i.e. cetomacrogol cream B.P.(F1), nonionic buttered cream (E.D.) (F2), anionic simple cream B.P. (F3), anionic buffered cream B.P. (F4), and the formulated nonionic cream base (F5). The creams were examined for antimicrobial activity against Staphylococcus aureus (S.aureus), Candida albians (C. albians ) and Propionibacterium acnes (P.ances) by agar diffusion method. The results showed that among the creams composed of 0.2% turmeric extract, only F3 could inhibit P.ances. The F2, F3, F4 and F5 containing 1.0% turmeric extract could inhibit S.aureus: The F5 containing 1% turmeric extract affected C. albians whereas F3 and F4 could inhibit P.ances. From the stability accelerated test, all creams containing 1.0% turmeric extract showed good physical stability.

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Published

2018-07-14

How to Cite

1.
Tharaswaeng S, Tipsombat R, Setakanna P, Tipsombat R, Mingmuang J. Effect of Cream Bases of Turmeric Cream on Antimicrobial Activity. Reg 4-5 Med J [internet]. 2018 Jul. 14 [cited 2025 Dec. 31];25(1):97-106. available from: https://he02.tci-thaijo.org/index.php/reg45/article/view/134484

Issue

Vol. 25 No. 1 (2006): January - March

Section

Original Article

License

ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์