A Comparative Study of Truncal Vagotomy with Pyloroplasty and Simple Closure with H2- Receptor Antagonist in the Treatment of Acute Pyloro-Duodenal Ulcer Perforation.

Abstract

          A comparative study between truncal vagotomy with pyloroplasty and simple closure with H₂-receptor antagonist was performed in 106 cases of acute pyloro-duodenal ulcer perforation at Makarak General Hospital during January 1996-December 2001. After 2-6 years of follow up it was found that there was no statistical difference in mean hospital stay, late relapsing symptoms, but the result of shorter operative time in simple closure was superior to the latter, with less problems of dumping syndrome and postvagotomy diarrhea. The results indicate that simple closure followed by drug therapy is acceptable treament for perforated pyloroduodenal ulcer.