Prevalence and Factors Associated with Laryngopharyngeal Reflux (LPR) among Patients Diagnosed with GERD in Samphran Hospital, Nakhon Pathom
Keywords:
gastroesophageal reflux disease, laryngopharyngeal refluxAbstract
Objectives: The purpose of this study was to evaluate the prevalence and factors associated with laryngopharyngeal reflux (LPR) among patients diagnosed with gastroesophageal reflux disease (GERD) in Samphran Hospital, Nakhon Pathom.
Method: This prospective study included patients diagnosed with GERD at outpatients department in Samphran Hospital. Sample size was 165 cases. We collected data from June 1, 2019 until completed. The data of the patients were collected by GERD questionnaire, reflux symptom index (RSI) questionnaire and laryngoscopy examination to evaluate reflux finding score (RFS). Baseline characteristics data were analyzed by using means, standard deviations and percentages. Analytic data were analyzed by using simple linear regression and multiple linear regression with 95% confidence interval, reflected a significance level at .05.
Results: There were 165 GERD patients. The mean age was 54 years (± 13.58), 131 (78.9%) cases were female. The mean body mass index (BMI) was 25.72 kg/m2 (± 6.81). The mean dinner-to-bed time was 2.06 hours (± 0.99). Prevalence of LPR among GERD patients was 47.4%. On simple and multiple linear regression analyses, positive correlation was observed between the GerdQ and RSI scores, RFS scores and RSI scores and BMI and RSI scores. Negative correlation was observed between dinner-to-bed time and RSI scores.
Conclusions: Prevalence of LPR among GERD patients in Samphran Hospital was 47.4%. LPR occurs and positively correlates with GERD but negatively correlates with dinner-to-bed time. Should physicians have awareness to recognize LPR when treating GERD patients because it prolongs recovery time.
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ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์
