Association Between Uncontrolled Blood Pressure and the Use of NSAIDs Among Hypertensive Patients at Khaoyoi Hospital, Petchaburi
Keywords:
hypertension, NSAIDs,, primary hypertension, complicationAbstract
Objectives: This study is to analyze the association between use of NSAIDs and uncontrolled blood pressure among primary hypertensive patients and to suggest options for patients who has symptoms that need NSAIDs.
Methods: A case-control study was conducted using the questionnaires and hospital database to collect data. Participants were patients diagnosed with primary hypertension and used of NSAIDs; who lived at Moo 5, Khaoyoi Subdistrict, Khaoyoi District, Petchaburi Province; during February 1 – March 31, 2021. Sample size was calculated by Epi Info program. Data were analyzed using excel and calculated in percentage and odds ratio at 95% confidence interval.
Results: Among 110 participants, there was 64.5% women and 35.5% men. The number of patients with poor control blood pressure and NSAIDs prescription was 40 compared to 16 patients who did not use NSAIDs. Twenty-eight patients whose blood pressure was within good control had NSAIDs prescription while 26 patients did not use NSAIDs. The odds ratio is 2.32 with 95% confidence interval (1.06, 5.11). Therefore, the association between poor controlled blood pressure and NSAIDs use was statistically significant.
Conclusion: The association between patients with poor controlled hypertension and use of NSAIDs is statistically significant. Moreover, elderly who have hypertension are more likely to use NSAIDs along with antihypertensive drugs. Therefore, NSAIDs should be prescribed only when needed or change to other option of pain killer such as paracetamol.
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ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์
