Prevalence of Obesity Among Children with Asthma and Outcomes of Treatment
Keywords:
childhood asthma, obesity among children with asthma, treatment outcomes of childhood asthmaAbstract
Asthma is a common chronic disease in children. Obesity is a significant risk factor that increases the severity of the disease. In Thailand, the prevalence of asthma in children is as high as 12.5% in those aged 13–14 years and 14.6% among aged 6–7 years. Asthma is also the most common chronic disease in the pediatric department at Somdej Phra Sangkharach the 17th Hospital. However, there is a lack of data on childhood asthma. Therefore, conducting this study to improve treatment efficiency is interested by the researcher.
Objective: The purpose is to determine the prevalence of obesity among children with asthma and to evaluate the treatment outcomes.
Methods: This retrospective descriptive study included childhood asthma aged 7–15 years who attended the pediatric asthma clinic at Somdej Phra Sangkharach the 17th Hospital from January 1, 2023, to December 31, 2023. Data were collected and analyzed included age, gender, weight, height, weight status, peak expiratory flow rate, predicted peak expiratory flow rate, emergency department visits, asthma-related hospitalization, length of hospital stay, and outcomes of treatment.
Results: The study included 48 patients. The prevalence of obesity among children with asthma in Somdej Phra Sangkharach the 17th Hospital was 14.6%. Obese children with asthma had significantly poorer asthma control compared to the non-obese. However, no significant differences were found in other outcomes.
Conclusion: Obese children with asthma have poorer asthma control compared to those without obesity. Therefore, developing specific treatment guidelines for this patient group is important, focusing on integrating weight management strategies alongside conventional asthma treatment protocols.
References
Peters U, Dixon AE, Forno E. Obesity and asthma. J Allergy Clin Immunol 2018;141(4):1169–79. doi: 10.1016/j.jaci.2018.02.004.
Chen Y-C, Su M-W, Brumpton BM, et al. Investigating obesity-related risk factors for childhood asthma. Pediatr Allergy Immunol 2021;33(1):1–8. doi: 10.1111/pai.13710.
Ahmadizar F, Vijverberg SJ, Arets HG, et al. Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis. Eur Respir J 2016;48(4):1063–73. doi: 10.1183/13993003.00766-2016.
Okubo Y, Nochioka K, Hataya H, et al. Burden of obesity on pediatric inpatients with acute asthma exacerbation in the United States. J Allergy Clin Immunol Pract 2016;4(6):1227–31. doi: 10.1016/j.jaip.2016.06.004.
Aragona E, El-Magbri E, Wang J, et al. Impact of obesity on clinical outcomes in urban children hospitalized for status asthmaticus. Hosp Pediatr 2016;6(4):211–8. doi: 10.1542/hpeds.2015-0094.
van Gent R, van der Ent CK, Rovers MM, et al. Excessive body weight is associated with additional loss of quality of life in children with asthma. J Allergy Clin Immunol 2007;119(3):591–6. doi: 10.1016/j.jaci.2006.11.007.
Forno E, Lescher R, Strunk R, et al. Decreased response to inhaled steroids in overweight and obese asthmatic children. J Allergy Clin Immunol 2011;127(3):741–9. doi: 10.1016/j.jaci.2010.12.010.
Chinratanapisit S, Vichyanond P. Despite progressive asthma guideline and increased access to medicine, asthma prevalence remains high. In: Mikkelsen B, Asher I, billo N, editors. The global asthma report 2022. New York: Global asthma network; 2022.
Pate CA, Zahran HS, Qin X, et al. Asthma surveillance - United States, 2006–2018. MMWR Surveill Summ 2021;70(5):1–32. doi: 10.15585/mmwr.ss7005a1.
Sanyaolu A, Okorie C, Qi X, et al. Childhood and adolescent obesity in the United States: a public health concern. Glob Pediatr Health 2019;6:1–11. doi: 10.1177/2333794X19891305
สำนักโภชนาการ กรมอนามัย กระทรวงสาธารณสุข. คู่มือการใช้เกณฑ์อ้างอิงการเจริญเติบโตของเด็กอายุ 6–19 ปี. พิมพ์ครั้งที่ 2. สมุทรปราการ: ทีเอส อินเตอร์พรินท์; 2564: 57–8.
Global initiative for asthma. Asthma management and prevention for adults, adolescents and children 6–11 years a pocket guide for health professionals (updated July 2023) [internet]. [cited 2024 August]. Available from: URL: ginasthma.org /wp-content/uploads/2023/07/GINA-2023-Pocket-Guide-WMS.pdf
Saskia G. Pulmonary and sleep medicine. In: Anderson CC, Kapoor S, Mark TE, editors. The Harriet lane handbook. 23rd ed. St. Petersburg: Elsevier; 2022: 644.
Balasubramanian S, Ravikumar NR, Chakkarapani E, et al. Peak expiratory flow rate in children - a ready reckoner. Indian Pediatr 2002;39(1):104–6.
Belamarich PF, Luder E, Kattan M, et al. Do obese inner-city children with asthma have more symptoms than nonobese children with asthma? Pediatrics 2000;106(6):1436–41. doi: 10.1542/peds.106.6.1436.
Sah PK, Gerald Teague W, Demuth KA, et al. Poor asthma control in obese children may be overestimated because of enhanced perception of dyspnea. J Allergy Clin Immunol Pract 2013;1(1):39–45. doi: 10.1016/j.jaip.2012.10.006.
Lang JE, Bunnell HT, Hossain MJ, et al. Being overweight or obese and the development of asthma. Pediatrics 2018;142(6):e20182119. doi: 10.1542/peds.2018-2119.
Hom J, Morley EJ, Sasso P, et al. Body mass index and pediatric asthma outcomes. Pediatr Emerg Care. 2009;25(9):569–71. doi: 10.1097/PEC.0b013e3181b4f639.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์
