Factors Associated with Acute Exacerbation of Asthma in Patients Attending Makarak Hospital, Kanchanaburi Province
Keywords:
acute exacerbation, asthma, factorAbstract
Objective: To study the factors associated with acute exacerbation of asthma in patients receiving care at Makarak Hospital, Kanchanaburi Province.
Method: A prospective analytical study was conducted by collecting data from asthma patients visiting Makarak Hospital between August 1, 2024 and March 31, 2025—a total period of 8 months. The research tool was a structured data collection form assessing factors related to acute asthma exacerbation. Data were presented as percentage, mean, and standard deviation. The factors were analyzed using independent t test and chi-square test.
Results: Among the 140 patients studied, significant factors associated with acute exacerbations included: low FEV1 %predicted (p = .006), history of severe exacerbation within the past 12 months (p < .001); poor asthma control according to “Asthma Control Test” (ACT), (p < .001); lack of prescription for inhaled corticosteroids (ICS), (p = .002); inhaler technique for using ICS (p < .001); and overuse of short-acting beta-agonists (SABA) (≥1 canisters per month) (p = .038).
Other factors; such as gender, obesity, blood eosinophil level, chronic allergic rhinitis and sinusitis, depression, history of intubation or ICU admission due to asthma, exposure to cigarette/e-cigarette smoke, and medication adherence based on “The Adherence to Asthma Medication Questionnaire” (AAMQ-13), were not significantly associated with acute exacerbations.
Conclusion: Key factors contributing to acute asthma exacerbations include: Asthma Control Test (ACT) score, low FEV1% predicted, history of severe exacerbation in the past 12 months, prescription of ICS, and overuse of SABA.
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ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์
