The overall survival and prognostic factors of palliative chemotherapy treatment (FOLFOX regimen) in patients with hepatocellular carcinoma at Sunpasitthiprasong Hospital, Ubon Ratchathani: Retrospective cohort study

Authors

  • Chayud Pruetlapakorn Department of Internal Medicine, Sunpasitthiprasong Hospital
  • Jitlada Juengsamarn Division of Medical Oncology, Department of Internal Medicine, Sunpasitthiprasong Hospital
  • Parinya Chamnan Cardio-metabolic Research Group, Department of Social Medicine, Sunpasitthiprasong Hospital

Keywords:

Hepatocellular carcinoma, FOLFOX, Chemotherapy

Abstract

Background: A large proportion of Thai patients with hepatocellular carcinoma presented with locally advanced or metastatic disease, which were ineligible for curative treatments. Although the multikinase inhibitors and immunotherapy was currently considered to a standard treatment for unresectable hepatocellular carcinoma, there were more Thai patients cannot be reached because of high medical expenses. So chemotherapy was one of choice for them to choose. Nowadays, there is a few data about the overall survival of Thai patients using FOLFOX.

Objective: This study aimed to assess overall survival and prognostic factors of palliative chemotherapy treatment in patients with hepatocellular carcinoma in Sunpasitthiprasong Hospital

Methods: A retrospective cohort study included patients with hepatocellular carcinoma who were admitted to Sunpasitthiprasong Hospital aged between 18 to 75 years old during October 1st, 2015 to December 31st, 2020. Clinical information was collected from the patient’s medical record which was diagnosed by AASLD practice guidelines. Mortality data was collected from

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Published

2023-09-29

How to Cite

Pruetlapakorn, C., Juengsamarn, J. ., & Chamnan, P. . (2023). The overall survival and prognostic factors of palliative chemotherapy treatment (FOLFOX regimen) in patients with hepatocellular carcinoma at Sunpasitthiprasong Hospital, Ubon Ratchathani: Retrospective cohort study. Sanpasitthiprasong Medical Journal, 44(2), 41–56. retrieved from https://he02.tci-thaijo.org/index.php/sanpasit_medjournal/article/view/258218

Issue

Vol. 44 No. 2 (2566): May-August

Section

original article

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