A study of survival rate and tumor location in metastatic colon cancer patients at Sunpasitthiprasong Hospital

Abstract

Background: Colon cancer is the third most common cancer among all cancer patients. Studies have found that the location of the colon cancer tumor is associated with different prognoses, which is believed to result from varying gene mutations. Current medical practice guidelines recommend considering the tumor location when determining the most appropriate treatment regimen for each patient. For metastatic colon cancer, the recommended treatment is chemotherapy combined with biologic agents to improve treatment efficacy. However, in Thailand, most patients currently do not have access to biologic agents, so chemotherapy alone remains the primary treatment. This situation prompted the present research, which aims to study the survival rate of Thai patients with metastatic colon cancer who received chemotherapy at Sunpasitthiprasong Hospital. The study also seeks to determine whether the location of the tumor is associated with survival outcomes. What are the factors related to survival rates in metastatic colon cancer patients? The findings from this research will serve as a valuable resource for improving the treatment of metastatic colon cancer patients and may contribute to the development of future treatment strategies for colon cancer overall.

Objective: To study the overall survival rate, the survival rates of patients with left- and right-sided tumors, and the factors associated with survival in patients with advanced colorectal cancer treated with FOLFOX chemotherapy at Sunpasitthiprasong Hospital.

Materials and Methods: This was a retrospective cohort study of metastatic colorectal cancer patients, aged 18–90 years, who received FOLFOX chemotherapy at Sunpasitthiprasong Hospital. All patients had biopsy-confirmed colorectal cancer and presented with appropriate