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Objective: A cross-sectional study design was conducted to assess the prevalence and factors associated with the
metabolic syndrome among HIV/AIDS infected patients in Nan Province, Thailand.
Methods: The study samples were drawn from antiretroviral clinics (ARV) at 10 district hospitals in Nan Province
from 2015-2016, aged ≥18 years, who had received antiretroviral therapy for at least six months.The metabolic
syndrome was assessed using the criteria of the National Cholesterol Education Program-Adult Treatment Panel
III (NCEP ATP III). A validated questionnaire and laboratory analysis were used as research instruments. Logistic
regression was used to identify the associations between variables at alpha=0.5.
Results: 252 HIV/AIDS patients who were on ARV were recruited into the study. 53.2% were males, average age was
41.3 years, 55.6% graduated from secondary school, and 51.9% had income ≤5,000 per month. 65.1% had received
ARV ≥25 months, and 87.7% had a CD4 level ≤ 200 cell/cm3, 23.4% had a high systolic blood pressure, and 29.4% had
a high diastolic blood pressure. 4.0% had high fasting blood glucose, 40.1% had a high triglyceride, 50.4% of males
had a low high density lipoprotein-cholesterol (HDL-cholesterol), and 78.6% of females had a low HDL-cholesterol.
The overall prevalence of metabolic syndrome was 52.8%. After control for all confounding variables, HIV/AIDS
patients aged 41-50 years had a 1.89 times greater chance (95%CI=1.07-3.33) to develop metabolic syndrome
compared to those aged <30 years old, and those aged ≥51years old had a greater chance 2.14 times (95%CI=1.12-
4.53) to develop metabolic syndrome than those aged <30 years old. Those who had no history of taking food more
than three times a day had a 1.96 times greater opportunity to develop metabolic syndrome (95%CI=1.19-3.24).
Conclusion: Thailand needs to set up a surveillance system on metabolic syndrome among HIV/AIDS infected
patients who use ARV to monitor prolonged side effects. Essential health information including personal healthy
dietary behavior should be provided for all ARV receiving patients.
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