The Association between Mammographic and Ultrasound Features and Histologic Grade in Invasive Ductal Carcinoma of the Breast

Authors

  • Voraparee Suvannarerg Department of Radiology
  • Woranuj Tangcharoensathien Thayarak Breast Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Shanigarn Thiravit Department of Radiology
  • Wasu Tanasoontrarat Department of Radiology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok 10300,
  • Kobkun Muangsomboon Department of Radiology
  • Pornpim Korparaphong Department of Radiology

Abstract

Objective: To evaluate the relationships between mammographic and ultrasound features and histological grades of invasive ductal carcinoma using the terminology of the fifth edition of Breast Imaging Reporting and Data System
(BI-RADS).
Methods: Mammographic and ultrasound features of invasive breast carcinomas diagnosed in 104 consecutive women between January 2011 and August 2014 were retrospectively reviewed, described according to the BI-RADS
lexicon, and correlated with histological tumor grade according to the Nottingham histologic scoring system.
Results: 104 invasive ductal carcinomas were graded histologically as follows: grade 1, 12.5%; grade 2, 50%; and grade 3, 37.5%. In multivariate analyses, mammographically identified oval or round shape of masses and indistinct
margin were significantly associated with grade 3 tumors (p < 0.05). In addition, ultrasound-identified microlobulated margin was significantly associated (p = 0.013) with grade 3 tumors. In contrast, mammographically identified
spiculated margin and ultrasound-identified posterior shadowing occurred significantly more frequently in grade 1 tumors (p < 0.05).
Conclusion: Mammographic and ultrasound features are effective predictors of histologic tumor grade of breast cancer.

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Published

07-06-2018

How to Cite

Suvannarerg, V., Tangcharoensathien, W., Thiravit, S., Tanasoontrarat, W., Muangsomboon, K., & Korparaphong, P. (2018). The Association between Mammographic and Ultrasound Features and Histologic Grade in Invasive Ductal Carcinoma of the Breast. Siriraj Medical Journal, 70(2), 152–158. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/127512

Issue

Vol. 70 No. 2 (2018): March-April

Section

Original Article

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